Regulation of Ras signal transduction during T cell development and activation.

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The Ras GTPase-activating protein neurofibromin 1 promotes the positive selection of thymocytes.Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.

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Regulation of Ras signal transduction during T cell development and activation.

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http://www.wikidata.org/entity/Q36435627

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Regulation of Ras signal transduction during T cell development and activation.

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Regulation of Ras signal transduction during T cell development and activation.

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type

Item

label

Regulation of Ras signal transduction during T cell development and activation.

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Regulation of Ras signal transduction during T cell development and activation.

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prefLabel

Regulation of Ras signal transduction during T cell development and activation.

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Regulation of Ras signal transduction during T cell development and activation.

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P1476

Regulation of Ras signal transduction during T cell development and activation

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P2093

Philip D King

http://www.w3.org/2001/XMLSchema#string

Philip E Lapinski

http://www.w3.org/2001/XMLSchema#string

P2860

RasGRP links T-cell receptor signaling to Ras

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow

Specificity in Ras and Rap signaling

RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses

Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

The GTPase superfamily: conserved structure and molecular mechanism

Mammalian MAP kinase signalling cascades

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

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147-153

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scholarly article

review article

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2012-01-01T00:00:00Z

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23205323

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P932

3510699

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Regulation of Ras signal transduction during T cell development and activation.

about

P2860

P2860

Regulation of Ras signal transduction during T cell development and activation.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P433

P478

P577

P698

P932

P1433

P1476

P2093

P2860

P304

P31

P433

P478

P577

P698

P932