Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels - Wikidata - wikimedia - TriplyDB

Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels

Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels

http://www.wikidata.org/entity/Q36436593

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Beta1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanisms Slo3 K+ channels: voltage and pH dependence of macroscopic currents Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channel On benzofuroindole analogues as smooth muscle relaxants Functional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channel Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradient.Role of KCNMA1 in breast cancer.Regulation of bestrophins by Ca2+: a theoretical and experimental study.A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification.Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels.Intra- and intersubunit cooperativity in activation of BK channels by Ca2+An S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gating Regulation of STREX exon large conductance, calcium-activated potassium channels by the beta4 accessory subunit.Cysteine modification alters voltage- and Ca(2+)-dependent gating of large conductance (BK) potassium channels.Differential effects of beta 1 and beta 2 subunits on BK channel activity.Gating and ionic currents reveal how the BKCa channel's Ca2+ sensitivity is enhanced by its beta1 subunit Distinct sensitivity of slo1 channel proteins to ethanol.Subunit-specific effect of the voltage sensor domain on Ca2+ sensitivity of BK channels.Locations of the beta1 transmembrane helices in the BK potassium channel The interface between membrane-spanning and cytosolic domains in Ca²+-dependent K+ channels is involved in β subunit modulation of gating.Measuring the influence of the BKCa {beta}1 subunit on Ca2+ binding to the BKCa channel.Transduction of voltage and Ca2+ signals by Slo1 BK channels.Mechanism of increased BK channel activation from a channel mutation that causes epilepsy.Ginsenoside Rg3 enhances large conductance Ca2+-activated potassium channel currents: a role of Tyr360 residue.The BK channel: a vital link between cellular calcium and electrical signaling.Molecular Determinants of BK Channel Functional Diversity and Functioning.Understanding the conformational motions of RCK gating rings.Four-turn alpha-helical segment prevents surface expression of the auxiliary hbeta2 subunit of BK-type channel.Lipids modulate the increase of BK channel calcium sensitivity by the β1 subunit Inactivation of the KcsA potassium channel explored with heterotetramers Statistical limits to the identification of ion channel domains by sequence similarity.Of fish oil, rafts, and scrambling things up.

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P2860

Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels

http://www.wikidata.org/entity/Q36436593

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Slo1 tail domains, but not the ...... a2+ sensitivity of BK channels

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Slo1 tail domains, but not the ...... a2+ sensitivity of BK channels

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type

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Slo1 tail domains, but not the ...... a2+ sensitivity of BK channels

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Slo1 tail domains, but not the ...... a2+ sensitivity of BK channels

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Slo1 tail domains, but not the ...... a2+ sensitivity of BK channels

@ast

Slo1 tail domains, but not the ...... a2+ sensitivity of BK channels

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P1433

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P1433

The Journal of General Physiology

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Slo1 tail domains, but not the ...... a2+ sensitivity of BK channels

@en

P2093

Brenda L Moss

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Crina M Nimigean

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Karl L Magleby

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Xiang Qian

http://www.w3.org/2001/XMLSchema#string

Xiaowei Niu

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P2860

Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: a transmembrane beta-subunit homolog

Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4

A neuronal beta subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to charybdotoxin and iberiotoxin

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

A novel calcium-sensing domain in the BK channel.

Large conductance voltage- and calcium-dependent K+ channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus

The beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting states

Determinant for beta-subunit regulation in high-conductance voltage-activated and Ca(2+)-sensitive K+ channels: an additional transmembrane region at the N terminus

Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel

Crystal structure and mechanism of a calcium-gated potassium channel

P304

829-843

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scholarly article

P356

10.1085/JGP.20028692

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6

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120

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270607483

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12451052

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2229562

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