Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development
about
Myb expression is critical for myeloid leukemia development induced by Setbp1 activation.Genomics of chronic neutrophilic leukemia.Somatic SETBP1 mutations in myeloid neoplasms.Only SETBP1 hotspot mutations are associated with refractory disease in myeloid malignancies.SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub.ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGFβ pathway genes through histone deacetylation
P2860
Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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name
Runx1 repression by histone de ...... e myeloid leukemia development
@ast
Runx1 repression by histone de ...... e myeloid leukemia development
@en
type
label
Runx1 repression by histone de ...... e myeloid leukemia development
@ast
Runx1 repression by histone de ...... e myeloid leukemia development
@en
prefLabel
Runx1 repression by histone de ...... e myeloid leukemia development
@ast
Runx1 repression by histone de ...... e myeloid leukemia development
@en
P2093
P2860
P356
P1433
P1476
Runx1 repression by histone de ...... e myeloid leukemia development
@en
P2093
B Przychodzen
H Makishima
J P Maciejewski
K O Gudmundsson
P2860
P2888
P304
P356
10.1038/LEU.2015.200
P577
2015-07-24T00:00:00Z