Mechanistic insights into editing-site specificity of ADARs.
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To edit or not to edit: regulation of ADAR editing specificity and efficiencyClick Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNAMechanisms of viral mutationAn efficient system for selectively altering genetic information within mRNAs.NanoStringDiff: a novel statistical method for differential expression analysis based on NanoString nCounter dataDNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA.Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2A Phenotypic Screen for Functional Mutants of Human Adenosine Deaminase Acting on RNA 1.Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes.ADAR2 affects mRNA coding sequence edits with only modest effects on gene expression or splicing in vivoStructures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivitySplicing variants of ADAR2 and ADAR2-mediated RNA editing in glioma.TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins.RNA-Seq analysis identifies a novel set of editing substrates for human ADAR2 present in Saccharomyces cerevisiae.ADAR regulates RNA editing, transcript stability, and gene expression.ADAR enzyme and miRNA story: a nucleotide that can make the difference.How do ADARs bind RNA? New protein-RNA structures illuminate substrate recognition by the RNA editing ADARs.Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans.Noncoding regions of C. elegans mRNA undergo selective adenosine to inosine deamination and contain a small number of editing sites per transcript.Switching Protein Localization by Site-Directed RNA Editing under Control of Light.Editing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome.Feasibility of occurrence of different types of protonated base pairs in RNA: a quantum chemical study.When MicroRNAs Meet RNA Editing in Cancer: A Nucleotide Change Can Make a Difference.Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.RNA editing with CRISPR-Cas13.Mechanistic Implications of Enhanced Editing by a HyperTRIBE RNA-binding protein.Site-directed RNA repair of endogenous Mecp2 RNA in neurons.Tertiary structural elements determine the extent and specificity of messenger RNA editing.Selective Recognition of RNA Substrates by ADAR Deaminase Domains.RNA-targeting CRISPR comes of age.Controlling the Editor: The Many Roles of RNA-Binding Proteins in Regulating A-to-I RNA Editing.How Does Mg2+ Modulate the RNA Folding Mechanism: A Case Study of the G:C W:W Trans Basepair.Base Flipping
P2860
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P2860
Mechanistic insights into editing-site specificity of ADARs.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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name
Mechanistic insights into editing-site specificity of ADARs.
@ast
Mechanistic insights into editing-site specificity of ADARs.
@en
type
label
Mechanistic insights into editing-site specificity of ADARs.
@ast
Mechanistic insights into editing-site specificity of ADARs.
@en
prefLabel
Mechanistic insights into editing-site specificity of ADARs.
@ast
Mechanistic insights into editing-site specificity of ADARs.
@en
P2860
P356
P1476
Mechanistic insights into editing-site specificity of ADARs.
@en
P2093
Ashani Kuttan
Brenda L Bass
P2860
P304
P356
10.1073/PNAS.1212548109
P407
P577
2012-11-05T00:00:00Z