about
High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligationBiosensors and their applications - A review.High Content Imaging (HCI) on Miniaturized Three-Dimensional (3D) Cell CulturesVisualizing cell architecture and molecular location using soft x-ray tomography and correlated cryo-light microscopyHigh-content screening in microfluidic devicesIntegrating high-content imaging and chemical genetics to probe host cellular pathways critical for Yersinia pestis infectionAutomated cell identification and tracking using nanoparticle moving-light-displaysAutomated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafishControlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responsesγ-H2AX kinetics as a novel approach to high content screening for small molecule radiosensitizersMultizone paper platform for 3D cell culturesIntroduction to the quantitative analysis of two-dimensional fluorescence microscopy images for cell-based screeningAssurance of monoclonality in one round of cloning through cell sorting for single cell deposition coupled with high resolution cell imagingHigh-throughput nonlinear optical microscopy.Future trends in screening technology for drug discovery.Multiscale models of angiogenesisAnisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarityVisualizing and clustering high throughput sub-cellular localization imagingThe response of fenestrations, actin, and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells.A functionalized poly(ethylene glycol)-based bioassay surface chemistry that facilitates bio-immobilization and inhibits non-specific protein, bacterial, and mammalian cell adhesion.Statistical and visual differentiation of subcellular imaging.Quantitative automated microscopy (QuAM) elucidates growth factor specific signalling in pain sensitizationHigh-throughput single-microparticle imaging flow analyzer.Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assayIntensity quantile estimation and mapping--a novel algorithm for the correction of image non-uniformity bias in HCS data.A Cell Derived Active Contour (CDAC) method for robust tracking in low frame rate, low contrast phase microscopy - an example: the human hNT astrocyte.Risk in CNS drug discovery: focus on treatment of Alzheimer's disease.Temporal Data Set Reduction Based on D-Optimality for Quantitative FLIM-FRET Imaging.Image-based screening for the identification of novel proteasome inhibitors.Fast automated cell phenotype image classificationFlow cytometry for drug discovery, receptor pharmacology and high-throughput screeningHigh-content single-cell drug screening with phosphospecific flow cytometry.Single cell cytometry of protein function in RNAi treated cells and in native populationsHigh-content live cell imaging with RNA probes: advancements in high-throughput antimalarial drug discovery.Miniaturized pre-clinical cancer models as research and diagnostic tools.Simultaneous detection of intracellular target and off-target binding of small molecule cancer drugs at nanomolar concentrations.A personal perspective on high-content screening (HCS): from the beginning.Integration of small-molecule discovery in academic biomedical researchComparison of multivariate data analysis strategies for high-content screening.A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Cellular imaging in drug discovery.
@ast
Cellular imaging in drug discovery.
@en
type
label
Cellular imaging in drug discovery.
@ast
Cellular imaging in drug discovery.
@en
prefLabel
Cellular imaging in drug discovery.
@ast
Cellular imaging in drug discovery.
@en
P2093
P2860
P356
P1476
Cellular imaging in drug discovery.
@en
P2093
Alexander Scheer
Anthony Nichols
Karen Yeow
P2860
P2888
P304
P356
10.1038/NRD2008
P577
2006-04-01T00:00:00Z