Influence of HLA-DR and -DQ alleles on autoantibody recognition of distinct epitopes within the juxtamembrane domain of the IA-2 autoantigen in type 1 diabetes

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Influence of HLA-DR and -DQ alleles on autoantibody recognition of distinct epitopes within the juxtamembrane domain of the IA-2 autoantigen in type 1 diabetes

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Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

@ast

Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

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Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

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Item

label

Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

@ast

Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

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Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

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Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

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Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

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Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

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P1154

2-s2.0-84953353333

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P1433

Diabetologia

P1476

Influence of HLA-DR and -DQ al ...... autoantigen in type 1 diabetes

@en

P2093

Carolyn C Richardson

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Diana Morgan

http://www.w3.org/2001/XMLSchema#string

Michael R Christie

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P2860

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

Humoral beta-cell autoimmunity in relation to HLA-defined disease susceptibility in preclinical and clinical type 1 diabetes.

Race-specific type 1 diabetes risk of HLA-DR7 haplotypes.

HLA-DR4-associated T and B cell responses to specific determinants on the IA-2 autoantigen in type 1 diabetes.

Etiology of type 1 diabetes.

Isolation and characterisation of a human monoclonal autoantibody to the islet cell autoantigen IA-2.

Relationships between major epitopes of the IA-2 autoantigen in Type 1 diabetes: Implications for determinant spreading.

HLA-DQ8 transgenic and NOD mice recognize different epitopes within the cytoplasmic region of the tyrosine phosphatase-like molecule, IA-2.

Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.

Autoantibodies to islet antigen-2 are associated with HLA-DRB1*07 and DRB1*09 haplotypes as well as DRB1*04 at onset of type 1 diabetes: the possible role of HLA-DQA in autoimmunity to IA-2.

P2888

s00125-015-3803-5

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334-340

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scholarly article

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10.1007/S00125-015-3803-5

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P433

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P478

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P50

Richard G Feltbower

Kerry A McLaughlin

P5530

4767621

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P577

2015-11-13T00:00:00Z

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283741107

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P6179

1040886625

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P6409

81759648

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P698

26564179

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P921

type-1 diabetes

autoantibody

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4705114

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P953

94828/