Beyond gap junctions: Connexin43 and bone cell signaling
about
Connexin 43 hemichannels and intracellular signaling in bone cellsDisruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging.Connexin mutant embryonic stem cells and human diseasesEvidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysisCx43 and mechanotransduction in bone.Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture.Prognostic impact of reduced connexin43 expression and gap junction coupling of neoplastic stromal cells in giant cell tumor of bonemiR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1.Connexins and pannexins in the skeleton: gap junctions, hemichannels and moreRole of connexins and pannexins during ontogeny, regeneration, and pathologies of boneDefective cancellous bone structure and abnormal response to PTH in cortical bone of mice lacking Cx43 cytoplasmic C-terminus domain.Connexins in the skeletonConnexin43 modulates post-natal cortical bone modeling and mechano-responsiveness.Inhibition of connexin 43 prevents trauma-induced heterotopic ossification.Mechanosignaling in bone health, trauma and inflammation.Osteocyte-driven bone remodeling.Negative influence of a long-term high-fat diet on murine bone architecture.High bone mass in mice lacking Cx37 because of defective osteoclast differentiation.Molecular mechanisms of osteoblast/osteocyte regulation by connexin43.Bone cell senescence: mechanisms and perspectives.Shifting paradigms on the role of connexin43 in the skeletal response to mechanical load.Sulfated glycosaminoglycans support osteoblast functions and concurrently suppress osteoclasts.An updated review of mechanotransduction in skin disorders: transcriptional regulators, ion channels, and microRNAs.Communication of cAMP by connexin43 gap junctions regulates osteoblast signaling and gene expressionThe response of osteoblastic MC3T3-E1 cells to micro- and nano-textured, hydrophilic and bioactive titanium surfaces.Osteocytic signalling pathways as therapeutic targets for bone fragility.Connexins and their channels in inflammation.Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation.Connexins and Pannexins in Bone and Skeletal Muscle.Inhibitors of connexin and pannexin channels as potential therapeutics.Mutual enhancement of differentiation of osteoblasts and osteocytes occurs through direct cell-cell contact.Yimu San improves obstetric ability of pregnant mice by increasing serum oxytocin levels and connexin 43 expression in uterine smooth muscle.Glucocorticoid Suppresses Connexin 43 Expression by Inhibiting the Akt/mTOR Signaling Pathway in Osteoblasts.Influence of the three-dimensional culture of human bone marrow mesenchymal stromal cells within a macroporous polysaccharides scaffold on Pannexin 1 and Pannexin 3.Connexin43 intercellular communication drives the early differentiation of human bone marrow stromal cells into osteoblasts.Impact of connexin 43 coupling on survival and migration of multiple myeloma cells.microRNAs and connexins in bone: interaction and mechanisms of delivery.The Expanding Life and Functions of Osteogenic Cells: From Simple Bone-Making Cells to Multifunctional Cells and Beyond.Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function.Ibandronate increases sclerostin levels and bone strength in male patients with idiopathic osteoporosis.
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P2860
Beyond gap junctions: Connexin43 and bone cell signaling
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Beyond gap junctions: Connexin43 and bone cell signaling
@ast
Beyond gap junctions: Connexin43 and bone cell signaling
@en
type
label
Beyond gap junctions: Connexin43 and bone cell signaling
@ast
Beyond gap junctions: Connexin43 and bone cell signaling
@en
prefLabel
Beyond gap junctions: Connexin43 and bone cell signaling
@ast
Beyond gap junctions: Connexin43 and bone cell signaling
@en
P2860
P1433
P1476
Beyond gap junctions: Connexin43 and bone cell signaling
@en
P2093
Lilian I Plotkin
P2860
P304
P356
10.1016/J.BONE.2012.09.030
P577
2012-10-02T00:00:00Z