Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
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Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 DonorsOptimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based DesignHigh-Throughput Sequencing-Based Immune Repertoire Study during Infectious DiseaseBroadly Neutralizing Antibodies for HIV EradicationA Little Help From the Follicles: Understanding the Germinal Center Response to Human Immunodeficiency Virus 1 Infection and Prophylactic Vaccines.Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Influenza immunization elicits antibodies specific for an egg-adapted vaccine strainFree Energy Perturbation Calculation of Relative Binding Free Energy between Broadly Neutralizing Antibodies and the gp120 Glycoprotein of HIV-1.A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data.Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation.Exceptional Antibodies Produced by Successive Immunizations.Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection.Spatiotemporal hierarchy in antibody recognition against transmitted HIV-1 envelope glycoprotein during natural infection.Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection.Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection.Distinct germinal center selection at local sites shapes memory B cell response to viral escapeMinimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.Likelihood-Based Inference of B Cell Clonal Families.Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis.Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants.Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.Optimal Sequential Immunization Can Focus Antibody Responses against Diversity Loss and Distraction.HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional PotencySpecifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.Conformational Epitope-Specific Broadly Neutralizing Plasma Antibodies Obtained from an HIV-1 Clade C-Infected Elite Neutralizer Mediate Autologous Virus Escape through Mutations in the V1 Loop.Maturational characteristics of HIV-specific antibodies in viremic individualsKey gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese DonorEarly Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose PatchHIV-1 clade C escapes broadly neutralizing autologous antibodies with N332 glycan specificity by distinct mechanismsSONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts.Optimal immunization cocktails can promote induction of broadly neutralizing Abs against highly mutable pathogens.Progress toward active or passive HIV-1 vaccination.Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors.Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies.New approaches to HIV vaccine development.Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments.HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies.
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Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Maturation and Diversity of th ...... rs of Chronic HIV-1 Infection.
@ast
Maturation and Diversity of th ...... rs of Chronic HIV-1 Infection.
@en
type
label
Maturation and Diversity of th ...... rs of Chronic HIV-1 Infection.
@ast
Maturation and Diversity of th ...... rs of Chronic HIV-1 Infection.
@en
prefLabel
Maturation and Diversity of th ...... rs of Chronic HIV-1 Infection.
@ast
Maturation and Diversity of th ...... rs of Chronic HIV-1 Infection.
@en
P2093
P2860
P50
P1433
P1476
Maturation and Diversity of th ...... rs of Chronic HIV-1 Infection.
@en
P2093
Baoshan Zhang
Chaim A Schramm
Gwo-Yu Chuang
Ivelin S Georgiev
Kevin O Saunders
Krisha McKee
Lawrence Shapiro
M Gordon Joyce
Mark Connors
Mark K Louder
P2860
P304
P356
10.1016/J.CELL.2015.03.004
P407
P577
2015-04-09T00:00:00Z