Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties
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Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channelsHyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsMechanosensitive gating of Kv channelsColocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cellsMolecular mechanism of voltage-dependent potentiation of KCNH potassium channelsThe activated state of a sodium channel voltage sensor in a membrane environmentHv1 proton channel opening is preceded by a voltage-independent transition.Probability fluxes and transition paths in a Markovian model describing complex subunit cooperativity in HCN2 channelsCytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.Properties of deactivation gating currents in Shaker channelsTwo centuries of memristors.Voltage-sensing phosphatase: actions and potentials.cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.Hysteresis of gating underlines sensitization of TRPV3 channels.Calcium influx through If channels in rat ventricular myocytes.Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor.Conductance hysteresis in the voltage-dependent anion channel.Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels.Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels.Kinetic relationship between the voltage sensor and the activation gate in spHCN channelsA novel mechanism of cone photoreceptor adaptation.Charge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate.Molecular mechanism for depolarization-induced modulation of Kv channel closure.Resting potential-dependent regulation of the voltage sensitivity of sodium channel gating in rat skeletal muscle in vivo.Free-energy relationships in ion channels activated by voltage and ligand.Retigabine holds KV7 channels open and stabilizes the resting potential.S4-based voltage sensors have three major conformationsReciprocal voltage sensor-to-pore coupling leads to potassium channel C-type inactivation.A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb.Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate.The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel.Hysteresis of ligand binding in CNGA2 ion channelsModulation of HCN channels in lateral septum by nicotine.Engineering a biological pacemaker: in vivo, in vitro and in silico modelsMolecular biology and biophysical properties of ion channel gating pores.Hysteresis in voltage-gated channelsHCN Channel C-Terminal Region Speeds Activation Rates Independently of Autoinhibition.Voltage-dependent opening of HCN channels: Facilitation or inhibition by the phytoestrogen, genistein, is determined by the activation status of the cyclic nucleotide gating ring.Low-conductance HCN1 ion channels augment the frequency response of rod and cone photoreceptors.Hysteresis of KcsA potassium channel's activation- deactivation gating is caused by structural changes at the channel's selectivity filter.
P2860
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P2860
Hysteresis in the voltage dependence of HCN channels: conversion between two modes affects pacemaker properties
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
Hysteresis in the voltage depe ...... s affects pacemaker properties
@ast
Hysteresis in the voltage depe ...... s affects pacemaker properties
@en
type
label
Hysteresis in the voltage depe ...... s affects pacemaker properties
@ast
Hysteresis in the voltage depe ...... s affects pacemaker properties
@en
prefLabel
Hysteresis in the voltage depe ...... s affects pacemaker properties
@ast
Hysteresis in the voltage depe ...... s affects pacemaker properties
@en
P2860
P356
P1476
Hysteresis in the voltage depe ...... s affects pacemaker properties
@en
P2093
H Peter Larsson
Shilpi Pandey
P2860
P304
P356
10.1085/JGP.200409130
P577
2005-02-14T00:00:00Z