Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways.
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Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese ratsArachidonic acid monooxygenase: Genetic and biochemical approaches to physiological/pathophysiological relevanceCytochrome P450 eicosanoids in hypertension and renal diseaseIncreased blood pressure in mice lacking cytochrome P450 2J5Epoxyeicosatrienoic Acid inhibition alters renal hemodynamics during pregnancyAngiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptationRegulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated ReceptorsPharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage.Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect.Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.Epoxyeicosatrienoic acid analog attenuates angiotensin II hypertension and kidney injury.High potassium intake enhances the inhibitory effect of 11,12-EET on ENaC.Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.Collecting duct principal cell transport processes and their regulation.Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive ratsOverexpression of G-protein-coupled receptor 40 enhances the mitogenic response to epoxyeicosatrienoic acidsEicosanoids, β-cell function, and diabetesEffects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)cAMP/PKA Pathways and S56 Phosphorylation Are Involved in AA/PGE2-Induced Increases in rNaV1.4 CurrentAngiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidneyAltered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease.Cathepsin B is secreted apically from Xenopus 2F3 cells and cleaves the epithelial sodium channel (ENaC) to increase its activity.Regulation of transport in the connecting tubule and cortical collecting ductDirect activation of ENaC by angiotensin II: recent advances and new insights.Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation.Failure to upregulate the adenosine2A receptor-epoxyeicosatrienoic acid pathway contributes to the development of hypertension in Dahl salt-sensitive rats.Epidermal growth factors in the kidney and relationship to hypertension.Epoxyeicosatrienoic acid activates BK channels in the cortical collecting ductArachidonic acid and ion channels: an updatePossible mediators of connecting tubule glomerular feedbackArachidonic acid inhibits basolateral K channels in the cortical collecting duct via cytochrome P-450 epoxygenase-dependent metabolic pathways.Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat.Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney.Role of cytochrome P450 epoxygenase in regulating renal membrane transport and hypertension.The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.Afferent Arteriolar Responses to β,γ-methylene ATP and 20-HETE are not Blocked by ENaC Inhibition.Cyp2c44 epoxygenase is essential for preventing the renal sodium absorption during increasing dietary potassium intake.Adenosine inhibits ENaC via cytochrome P-450 epoxygenase-dependent metabolites of arachidonic acid.Orally Active Epoxyeicosatrienoic Acid Analogs.Epithelial Na+ Channel Regulation by Extracellular and Intracellular Factors.
P2860
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P2860
Arachidonic acid inhibits epithelial Na channel via cytochrome P450 (CYP) epoxygenase-dependent metabolic pathways.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
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2004年學術文章
@zh-hant
name
Arachidonic acid inhibits epit ...... -dependent metabolic pathways.
@ast
Arachidonic acid inhibits epit ...... -dependent metabolic pathways.
@en
type
label
Arachidonic acid inhibits epit ...... -dependent metabolic pathways.
@ast
Arachidonic acid inhibits epit ...... -dependent metabolic pathways.
@en
prefLabel
Arachidonic acid inhibits epit ...... -dependent metabolic pathways.
@ast
Arachidonic acid inhibits epit ...... -dependent metabolic pathways.
@en
P2093
P2860
P356
P1476
Arachidonic acid inhibits epit ...... -dependent metabolic pathways.
@en
P2093
Alberto Nasjletti
Dao-Hong Lin
Ganesh S S Yaddanapudi
John R Falck
Rowena Kemp
Wen-Hui Wang
P2860
P304
P356
10.1085/JGP.200409140
P577
2004-11-15T00:00:00Z