Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature
about
Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis.A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formationCollaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targetingTargeted delivery of therapeutics to endothelium.Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.Targeting recombinant thrombomodulin fusion protein to red blood cells provides multifaceted thromboprophylaxis.A humanized single-chain variable fragment antibody against beta3 integrin in Escherichia coliTargeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysisDynamic changes of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) on pulmonary injury induced by ischemia-reperfusion in rats.Targeted endothelial delivery of nanosized catalase immunoconjugates protects lung grafts donated after cardiac death.Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation.Modulation of endothelial targeting by size of antibody-antioxidant enzyme conjugates.Targeting antioxidant and antithrombotic biotherapeutics to endothelium.Targeted modulation of reactive oxygen species in the vascular endotheliumEndogenously generated plasmin at the vascular wall injury site amplifies lysine binding site-dependent plasminogen accumulation in microthrombi.Endothelial targeting of antibody-decorated polymeric filomicelles.Collaborative Enhancement of Endothelial Targeting of Nanocarriers by Modulating Platelet-Endothelial Cell Adhesion Molecule-1/CD31 Epitope Engagement.Advanced drug delivery systems for antithrombotic agents.Platelet endothelial cell adhesion molecule targeted oxidant-resistant mutant thrombomodulin fusion protein with enhanced potency in vitro and in vivo.Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1.Targeted therapeutics and nanodevices for vascular drug delivery: quo vadis?Lung vascular targeting through inhalation delivery: insight from filamentous viruses and other shapes.Vascular targeting of antithrombotic agents.Acute lung injury and pulmonary vascular permeability: use of transgenic models.Endothelial nanomedicine for the treatment of pulmonary disease.Targeted endothelial nanomedicine for common acute pathological conditions.Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1.The spatial dynamics of fibrin clot dissolution catalyzed by erythrocyte-bound vs. free fibrinolytics.
P2860
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P2860
Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Prophylactic thrombolysis by t ...... 1 in the pulmonary vasculature
@ast
Prophylactic thrombolysis by t ...... 1 in the pulmonary vasculature
@en
type
label
Prophylactic thrombolysis by t ...... 1 in the pulmonary vasculature
@ast
Prophylactic thrombolysis by t ...... 1 in the pulmonary vasculature
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prefLabel
Prophylactic thrombolysis by t ...... 1 in the pulmonary vasculature
@ast
Prophylactic thrombolysis by t ...... 1 in the pulmonary vasculature
@en
P2093
P2860
P1433
P1476
Prophylactic thrombolysis by t ...... 1 in the pulmonary vasculature
@en
P2093
Aron B Fisher
Bi-Sen Ding
Claudia Gottstein
Douglas B Cines
Juan-Carlos Murciano
Kumkum Ganguly
Melpo Christofidou-Solomidou
Nankang Hong
Steven M Albelda
Vladimir R Muzykantov
P2860
P304
P356
10.1182/BLOOD-2007-07-103002
P407
P577
2007-11-28T00:00:00Z