Mutational specificity and genetic control of replicative bypass of an abasic site in yeast
about
Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1DNA Synthesis across an Abasic Lesion by Human DNA Polymerase ιReplication through an abasic DNA lesion: structural basis for adenine selectivityDNA Synthesis across an Abasic Lesion by Yeast Rev1 DNA PolymeraseLearning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activityAmino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA PolymeraseContribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNATranslesion synthesis of abasic sites by yeast DNA polymerase epsilon.A novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiaeDNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeRequirement of Rad5 for DNA polymerase zeta-dependent translesion synthesis in Saccharomyces cerevisiaeSerial analysis of mutation spectra (SAMS): a new approach for the determination of mutation spectra of site-specific DNA damage and their sequence dependenceYeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrationsMitochondrial DNA toxicity in forebrain neurons causes apoptosis, neurodegeneration, and impaired behaviorA single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast.Translesion synthesis across abasic lesions by human B-family and Y-family DNA polymerases α, δ, η, ι, κ, and REV1Requirement of replication checkpoint protein kinases Mec1/Rad53 for postreplication repair in yeastMechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.Role of AtPolζ, AtRev1 and AtPolη in γ ray-induced mutagenesisReplicative bypass of abasic site in Escherichia coli and human cells: similarities and differencesPre-steady state kinetic studies show that an abasic site is a cognate lesion for the yeast Rev1 protein.The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites.DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA.Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ.Mechanisms of glycosylase induced genomic instabilityThe mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast.Yeast Rev1 protein promotes complex formation of DNA polymerase zeta with Pol32 subunit of DNA polymerase deltaThe choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis.Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polzeta-dependent mechanism.The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast.DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures.High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells.Roles of Rev1, Pol zeta, Pol32 and Pol eta in the bypass of chromosomal abasic sites in Saccharomyces cerevisiae.REV1 restrains DNA polymerase zeta to ensure frame fidelity during translesion synthesis of UV photoproducts in vivoParticipation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in yeast Saccharomyces cerevisiae.Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.Effect of sequence context and direction of replication on AP site bypass in Saccharomyces cerevisiae.A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain.PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration.Monitoring bypass of single replication-blocking lesions by damage avoidance in the Escherichia coli chromosome.
P2860
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P2860
Mutational specificity and genetic control of replicative bypass of an abasic site in yeast
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
@zh-hant
name
Mutational specificity and gen ...... ass of an abasic site in yeast
@ast
Mutational specificity and gen ...... ass of an abasic site in yeast
@en
type
label
Mutational specificity and gen ...... ass of an abasic site in yeast
@ast
Mutational specificity and gen ...... ass of an abasic site in yeast
@en
prefLabel
Mutational specificity and gen ...... ass of an abasic site in yeast
@ast
Mutational specificity and gen ...... ass of an abasic site in yeast
@en
P2093
P2860
P356
P1476
Mutational specificity and gen ...... ass of an abasic site in yeast
@en
P2093
Louise Prakash
Robert E Johnson
Satya Prakash
P2860
P304
P356
10.1073/PNAS.0711227105
P407
P577
2008-01-17T00:00:00Z