Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations. - Wikidata - wikimedia - TriplyDB

Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations.

Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations.

http://www.wikidata.org/entity/Q36446526

about

Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders Why boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiation Pharmacogenomics of human P450 oxidoreductase Shedding light on protein folding, structural and functional dynamics by single molecule studies Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro Pharmacogenomic discovery using cell-based models Influence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6 Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation.The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients.Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicity Heme oxygenase isoforms differ in their subcellular trafficking during hypoxia and are differentially modulated by cytochrome P450 reductase.Malformation syndromes caused by disorders of cholesterol synthesis.Pharmacogenetics in Jewish populations.Identification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations.Concomitant mutations in the P450 oxidoreductase and androgen receptor genes presenting with 46,XY disordered sex development and androgenization at adrenarche.Transcriptional regulation of the human P450 oxidoreductase gene: hormonal regulation and influence of promoter polymorphisms.High-yield expression of a catalytically active membrane-bound protein: human P450 oxidoreductase.Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.Identification of cytochrome P450 oxidoreductase gene variants that are significantly associated with the interindividual variations in warfarin maintenance dose.Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium.Functional POR A503V is associated with the risk of bladder cancer in a Chinese population.Multigene predictors of tacrolimus exposure in kidney transplant recipients.Molecular Cloning, Expression Pattern and Polymorphisms of NADPH-Cytochrome P450 Reductase in the Bird Cherry-Oat Aphid Rhopalosiphum padi (L.).Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.Genotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency Consequences of POR mutations and polymorphisms.Genetic variations in NADPH-CYP450 oxidoreductase in a Czech Slavic cohort.NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem The common P450 oxidoreductase variant A503V is not a modifier gene for 21-hydroxylase deficiency Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency.Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver.The POR rs1057868-rs2868177 GC-GT diplotype is associated with high tacrolimus concentrations in early post-renal transplant recipients.Nomenclature for alleles of the cytochrome P450 oxidoreductase gene.Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients Clinical, genetic, and enzymatic characterization of P450 oxidoreductase deficiency in four patients.Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks.Cytochrome P450 oxidoreductase deficiency caused by R457H mutation in POR gene in Chinese: case report and literature review.

P2860

Q24607331-4747C15E-1E99-435E-BF80-126418BDDFBD Q24609157-53D735A3-1E47-4C47-B6F4-E277DD8AC3FA Q24613957-EFBD0EDD-EBFF-4A6B-AD6C-96B3A4CF64BB Q24618043-01D78505-D268-4F24-AF8E-B637A9860099 Q26998463-43C83305-1B61-4329-BB27-BE08AF92C955 Q26999437-8CE25A42-780F-4479-84B5-52854CA05690 Q28295439-27C3239C-0408-4594-A89A-9BAB61778FA6 Q28392982-B40B3431-5928-4DED-8AFE-B1831F17F696 Q28484196-BAD87689-793F-4850-9FC1-1BD93B93646F Q33431427-6825F98C-16AD-452F-A5BA-73790E33F890 Q33628473-BF0BE6AB-2B92-43B7-9617-A7432FBEC02A Q34181972-2C0A79C3-3757-4A00-B20E-B2FD641F2F69 Q34251131-C7A08E24-0ACA-4344-9423-899C7FEEC0A5 Q34395171-9DD13D2E-DEFF-4805-A8E1-2E3A27F2B232 Q34458720-EE3B4FA0-5570-4940-8307-268451DA5F17 Q34731517-E286BE01-78AA-4848-977F-977DA9AC003C Q34766752-35752DF3-9439-4F39-AB1B-B18057B9CEC7 Q34856488-FEAD446D-3558-4FE4-887E-E0359B2584ED Q35046889-07140139-BE8F-48D8-B09F-9678B470106D Q35071437-C1930298-0E67-4744-8D79-5E0B30B0E1B2 Q35122798-EC5918BB-75B0-41B3-875A-E09B92EA7B82 Q35176142-128AE406-4774-4A11-A3A0-A56ABD408492 Q35796654-941D3C26-6B8C-490F-868E-2A662B9C5A0D Q35924246-BD8183DD-888F-491B-A976-30E2A92E3745 Q36001940-8395F383-4C89-4B5C-A08B-95391E7C5DCC Q36007003-13336D89-6339-4979-8433-22A6B697DF23 Q36049127-E6FF31A0-EF5E-4001-9392-D98C8CF551FF Q36248030-3BD4F777-E2A3-422B-911A-D1F64EA085EE Q36326565-6D4B15E1-B8CE-45BA-B2A0-E0A838C3FF3F Q36497649-DED998D9-C301-4A41-A306-666B5A425AA7 Q36634077-FB03DF55-9BB9-46D8-A9F3-7CF23352165C Q36755276-053D5B40-BDC0-41F7-BF65-1902CF7F0F97 Q37072683-BC863746-E8A1-4AD1-90C7-74A5C18411EC Q37179263-0094F224-1BD0-4431-9F97-84826775CC73 Q37254607-DC4AC24D-3D2A-4A0B-BCD9-71E98F155BD0 Q37365498-D65BA60F-4BCF-4CFC-A364-5F1089F9773D Q37439873-95B9F85C-F6AE-4873-AD01-B1AA3F700543 Q37482676-25C27AE4-DD23-4AF5-AEAF-8A4E92089ED6 Q37678060-7053A789-1E46-4C2E-A9AB-88F285C3E262 Q37698004-EA2A3DEE-A37D-43FF-824B-82B7CD5DEB74

P2860

Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations.

http://www.wikidata.org/entity/Q36446526

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Genetics of P450 oxidoreductas ...... ties of 15 missense mutations.

@ast

Genetics of P450 oxidoreductas ...... ties of 15 missense mutations.

@en

type

label

Genetics of P450 oxidoreductas ...... ties of 15 missense mutations.

@ast

Genetics of P450 oxidoreductas ...... ties of 15 missense mutations.

@en

prefLabel

Genetics of P450 oxidoreductas ...... ties of 15 missense mutations.

@ast

Genetics of P450 oxidoreductas ...... ties of 15 missense mutations.

@en

P1433

Q36446526-B66F5FFA-4BB1-434E-B81C-0DFE86F6CFE3

P1476

Q36446526-4607E673-DFFE-4088-A4D8-7269E29E27E0

P2093

Q36446526-01240E4E-90E1-42FF-8208-87EDD26ECE5D

Q36446526-3AC524BC-8339-4457-9C1E-9614ADC2B547

Q36446526-D9CAF87E-008B-4C52-A9AA-A06C4F7A0623

Q36446526-E858C7C8-EEC7-42C7-97B6-CA696B1EDC66

P2860

Q36446526-008C2CC0-C5CB-40E9-B285-C2F3E58FBC91

Q36446526-0FC04580-68A8-467F-B813-26224114B8BC

Q36446526-20FAA336-A34D-4158-AAA0-BD827C3B9438

Q36446526-308CDE3C-A1D4-4F96-B754-5525E9B5EBA3

Q36446526-322DD549-4662-4083-97C8-CBCB996C6F16

Q36446526-4904991C-A3C9-4D82-91C9-CD748594497A

Q36446526-4C626E3B-4F3D-4C30-9AF3-391C1958F032

Q36446526-5E03ADC2-86AE-4B03-BD05-6B58B429E1A8

Q36446526-7451B611-43D4-4A34-A645-D67752A28D16

Q36446526-779485B9-B757-4DDE-8F37-D4B42CFDFB2D

P304

Q36446526-9BBC167C-6AFE-46AA-B616-6ACAF0A5A06F

P31

Q36446526-56C4CD02-C117-488C-8B40-1BD265D1EA25

P356

Q36446526-9AC36143-FC49-4474-9799-DBD1E1403EC8

P407

Q36446526-5F7B6D73-6695-4649-B2C9-2446FF6B0847

P433

Q36446526-E7D8A22F-A022-4F46-9C2D-51C1C0E1085D

P478

Q36446526-4220FA18-6A3B-451B-8D2A-FCCCEC5617A8

P577

Q36446526-9326AD86-7126-4C5B-9167-E72EAE94FCE7

P5875

Q36446526-79BB09F2-ADD1-4AB8-A134-0EFDA28FF2BF

P698

Q36446526-3BD82ECC-641B-46B0-98C5-D600426CDBB4

P932

Q36446526-7C626E45-CA2D-45F6-A953-78C1E8210DA8

P356

PNAS.0711621105

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Genetics of P450 oxidoreductas ...... ties of 15 missense mutations.

@en

P2093

Kathleen M Giacomini

http://www.w3.org/2001/XMLSchema#string

Ningwu Huang

http://www.w3.org/2001/XMLSchema#string

Vishal Agrawal

http://www.w3.org/2001/XMLSchema#string

Walter L Miller

http://www.w3.org/2001/XMLSchema#string

P2860

Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis

Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes

Characterization of single-nucleotide polymorphisms in coding regions of human genes

Association of multiple developmental defects and embryonic lethality with loss of microsomal NADPH-cytochrome P450 oxidoreductase

Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17

Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components

Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study

Modulation of human CYP19A1 activity by mutant NADPH P450 oxidoreductase

P304

1733-1738

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0711621105

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

105

http://www.w3.org/2001/XMLSchema#string

P577

2008-01-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5620721

http://www.w3.org/2001/XMLSchema#string

P698

18230729

http://www.w3.org/2001/XMLSchema#string

P932

2234213

http://www.w3.org/2001/XMLSchema#string