MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors
about
Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.Novel Structural Approaches to Study GPCR RegulationKLHL12 Promotes Non-Lysine Ubiquitination of the Dopamine Receptors D4.2 and D4.4, but Not of the ADHD-Associated D4.7 VariantHERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stabilityAgonist-promoted ubiquitination differentially regulates receptor trafficking of endothelin type A and type B receptorsUbiquitination and degradation of CFTR by the E3 ubiquitin ligase MARCH2 through its association with adaptor proteins CAL and STX6Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress.Potent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5Agonist binding to β-adrenergic receptors on human airway epithelial cells inhibits migration and wound repair.Carvedilol binding to β2-adrenergic receptors inhibits CFTR-dependent anion secretion in airway epithelial cellsUbiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.Distinct G protein-coupled receptor recycling pathways allow spatial control of downstream G protein signaling.MARCH2 regulates autophagy by promoting CFTR ubiquitination and degradation and PIK3CA-AKT-MTOR signalingActivation of the cAMP/PKA pathway induces UT-A1 urea transporter monoubiquitination and targets it for lysosomal degradationClass B β-arrestin2-dependent CCR5 signalosome retention with natural antibodies to CCR5.Ubiquitin-dependent sorting in endocytosis.Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress.Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction.The Membrane Associated RING-CH Proteins: A Family of E3 Ligases with Diverse Roles through the Cell.GPCR desensitization: Acute and prolonged phases.G Protein-Coupled Receptor Signaling Through β-Arrestin-Dependent Mechanisms.Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.Regulation of G Protein-Coupled Receptors by Ubiquitination.The Role of Natural Antibodies to CC Chemokine Receptor 5 in HIV Infection.
P2860
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P2860
MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors
description
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name
MARCH2 promotes endocytosis an ...... ound β(2)-adrenergic receptors
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MARCH2 promotes endocytosis an ...... ound β(2)-adrenergic receptors
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type
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MARCH2 promotes endocytosis an ...... ound β(2)-adrenergic receptors
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MARCH2 promotes endocytosis an ...... ound β(2)-adrenergic receptors
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prefLabel
MARCH2 promotes endocytosis an ...... ound β(2)-adrenergic receptors
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MARCH2 promotes endocytosis an ...... ound β(2)-adrenergic receptors
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P2093
P2860
P356
P1476
MARCH2 promotes endocytosis an ...... ound β(2)-adrenergic receptors
@en
P2093
James W Wisler
Jiao-Hui Wu
Kunhong Xiao
Neil J Freedman
Sang-oh Han
Sudha K Shenoy
P2860
P304
P356
10.1083/JCB.201208192
P407
P577
2012-11-19T00:00:00Z