Family-based designs in the age of large-scale gene-association studies.
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Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1Assessment of Alzheimer's disease case-control associations using family-based methodsEvidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palateGenetic linkage analysis in the age of whole-genome sequencingGenetic factors influencing risk to orofacial clefts: today's challenges and tomorrow's opportunitiesGenetic & epigenetic approach to human obesityAssociation of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disordersGenome-wide association study in German patients with attention deficit/hyperactivity disorder.A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population.A systems biology approach using metabolomic data reveals genes and pathways interacting to modulate divergent growth in cattle.Rare-variant extensions of the transmission disequilibrium test: application to autism exome sequence data.Comparing the power of family-based association tests for sequence data with applications in the GAW18 simulated data.PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder populationA re-formulation of generalized linear mixed models to fit family data in genetic association studies.A computational method for genotype calling in family-based sequencing dataAn evaluation of power and type I error of single-nucleotide polymorphism transmission/disequilibrium-based statistical methods under different family structures, missing parental data, and population stratification.Detecting multiple variants associated with disease based on sequencing data of case-parent trios.Estimating ethnic admixture from pedigree data.Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data.A family-based likelihood ratio test for general pedigree structures that allows for genotyping error and missing data.Comparing strategies for evaluation of candidate genes in case-control studies using family dataUnraveling the genetics of human obesity.The Fangshan/Family-based Ischemic Stroke Study In China (FISSIC) protocol.Pesticide exposure and risk of Parkinson's disease: a family-based case-control studyApplication of the Linux cluster for exhaustive window haplotype analysis using the FBAT and Unphased programs.Density of common complex ocular traits in the aging eye: analysis of secondary traits in genome-wide association studiesScreening and replication using the same data set: testing strategies for family-based studies in which all probands are affectedOn combining triads and unrelated subjects data in candidate gene studies: an application to data on testicular cancer.A novel tool for individual haplotype inference using mixed data.Comprehensive linkage and association analyses identify haplotype, near to the TNFSF15 gene, significantly associated with spondyloarthritisA Bayesian approach to efficient differential allocation for resampling-based significance testing.Univariate/multivariate genome-wide association scans using data from families and unrelated samples.A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia.Parsing the effects of individual SNPs in candidate genes with family data.Magnitude of stratification in human populations and impacts on genome wide association studies.GEE-based SNP set association test for continuous and discrete traits in family-based association studiesEstimating gene penetrance from family data.Is the gene-environment interaction paradigm relevant to genome-wide studies? The case of education and body mass index.Rs12970134 near MC4R is associated with appetite and beverage intake in overweight and obese children: A family-based association study in Chinese population.
P2860
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P2860
Family-based designs in the age of large-scale gene-association studies.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Family-based designs in the age of large-scale gene-association studies.
@ast
Family-based designs in the age of large-scale gene-association studies.
@en
type
label
Family-based designs in the age of large-scale gene-association studies.
@ast
Family-based designs in the age of large-scale gene-association studies.
@en
prefLabel
Family-based designs in the age of large-scale gene-association studies.
@ast
Family-based designs in the age of large-scale gene-association studies.
@en
P356
P1476
Family-based designs in the age of large-scale gene-association studies.
@en
P2093
Christoph Lange
P2888
P304
P356
10.1038/NRG1839
P50
P577
2006-05-01T00:00:00Z