about
Mechanism of T cell tolerance induced by myeloid-derived suppressor cells.Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune diseaseIndirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1.Molecular underpinning of B-cell anergy.Defects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells.Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade.Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival.Downregulation of Orai1 expression in the airway alleviates murine allergic rhinitisTranscriptional regulation of T cell tolerance.Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cellsTec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkA signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways.A role for IRF8 in B cell anergy.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Calcium Signaling: From Normal B Cell Development to Tolerance Breakdown and Autoimmunity.The bullseye synapse formed between CD4+ T-cell and staphylococcal enterotoxin B-pulsed dendritic cell is a suppressive synapse in T-cell response.Up-regulation of FOXP3 and induction of suppressive function in CD4+ Jurkat T-cells expressing hepatitis C virus core protein.Control of virus-specific CD8+ T-cell exhaustion and immune-mediated pathology by E3 ubiquitin ligase Cbl-b during chronic viral infection.Upregulation of store-operated Ca(2+) entry in the naïve CD4(+) T cells with aberrant cytokine releasing in active rheumatoid arthritis.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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2006年學術文章
@zh-hant
name
Transcriptional basis of lymphocyte tolerance.
@ast
Transcriptional basis of lymphocyte tolerance.
@en
type
label
Transcriptional basis of lymphocyte tolerance.
@ast
Transcriptional basis of lymphocyte tolerance.
@en
prefLabel
Transcriptional basis of lymphocyte tolerance.
@ast
Transcriptional basis of lymphocyte tolerance.
@en
P2093
P2860
P1476
Transcriptional basis of lymphocyte tolerance
@en
P2093
Anjana Rao
Madhuri Borde
Michael C Carroll
Robert A Barrington
P2860
P304
P356
10.1111/J.0105-2896.2006.00370.X
P577
2006-04-01T00:00:00Z