Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles.
about
Role of TET enzymes in DNA methylation, development, and cancerCaspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent mannerASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.New insights into transcriptional and leukemogenic mechanisms of AML1-ETO and E2A fusion proteins.TET2 in Normal and Malignant Hematopoiesis.Epigenetic dysregulation of hematopoietic stem cells and preleukemic state.Next-generation sequencing with a myeloid gene panel in core-binding factor AML showed KIT activation loop and TET2 mutations predictive of outcome.Immortalization of human AE pre-leukemia cells by hTERT allows leukemic transformation.SHP2 is required for BCR-ABL1-induced hematologic neoplasia.RUNX1-ETO Leukemia.Recent advances in the understanding and treatment of acute myeloid leukemia
P2860
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P2860
Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
Integrative genetic analysis o ...... s cooperating disease alleles.
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Integrative genetic analysis o ...... s cooperating disease alleles.
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type
label
Integrative genetic analysis o ...... s cooperating disease alleles.
@ast
Integrative genetic analysis o ...... s cooperating disease alleles.
@en
prefLabel
Integrative genetic analysis o ...... s cooperating disease alleles.
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Integrative genetic analysis o ...... s cooperating disease alleles.
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P2093
P2860
P50
P356
P1476
Integrative genetic analysis o ...... es cooperating disease alleles
@en
P2093
Alan H Shih
Benjamin G Neel
Bridget Riley-Gillis
Dayna M Oschwald
Ewa A Grabowska
Francesca Voza
Jacob E Joergens
Kanika Arora
Megan A Hatlen
P2860
P356
10.1084/JEM.20150524
P407
P577
2015-12-14T00:00:00Z