Manipulation of the membrane binding site of vitamin K-dependent proteins: enhanced biological function of human factor VII.
about
Mutagenesis of the gamma-carboxyglutamic acid domain of human factor VII to generate maximum enhancement of the membrane contact site.Recombinant factor VIIa analog NN1731 (V158D/E296V/M298Q-FVIIa) enhances fibrin formation, structure and stability in lipidated hemophilic plasma.Accelerating membrane insertion of peripheral proteins with a novel membrane mimetic model.Factor VII and protein C are phosphatidic acid-binding proteins.Elevated function of blood clotting factor VIIa mutants that have enhanced affinity for membranes. Behavior in a diffusion-limited reaction.Enhancement of human protein C function by site-directed mutagenesis of the gamma-carboxyglutamic acid domain.
P2860
Manipulation of the membrane binding site of vitamin K-dependent proteins: enhanced biological function of human factor VII.
description
1998 nî lūn-bûn
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1998年の論文
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1998年学术文章
@wuu
1998年学术文章
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1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
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1998年學術文章
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name
Manipulation of the membrane b ...... function of human factor VII.
@ast
Manipulation of the membrane b ...... function of human factor VII.
@en
type
label
Manipulation of the membrane b ...... function of human factor VII.
@ast
Manipulation of the membrane b ...... function of human factor VII.
@en
prefLabel
Manipulation of the membrane b ...... function of human factor VII.
@ast
Manipulation of the membrane b ...... function of human factor VII.
@en
P2093
P2860
P356
P1476
Manipulation of the membrane b ...... function of human factor VII.
@en
P2093
D C Foster
G L Nelsestuen
P2860
P304
P356
10.1073/PNAS.95.8.4229
P407
P577
1998-04-01T00:00:00Z