Modelling dynamics in protein crystal structures by ensemble refinement
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Uncertainty in integrative structural modelingThe ensemble nature of allosteryAutomated identification of functional dynamic contact networks from X-ray crystallographyIntegrated description of protein dynamics from room-temperature X-ray crystallography and NMREnsemble refinement shows conformational flexibility in crystal structures of human complement factor DCrystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFRIncorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discoveryThe R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structuresStructural and functional studies on a thermostable polyethylene terephthalate degrading hydrolase from Thermobifida fuscaInsights into the structure and function of fungal β-mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzymeStructure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EMThe role of protein dynamics in the evolution of new enzyme functionIdentifying and Visualizing Macromolecular Flexibility in Structural BiologyIntegrative, dynamic structural biology at atomic resolution--it's about timeExposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFitA multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron densityEnsemble MD simulations restrained via crystallographic data: accurate structure leads to accurate dynamicsResidue-level global and local ensemble-ensemble comparisons of protein domains.Active site and laminarin binding in glycoside hydrolase family 55Measuring and modeling diffuse scattering in protein X-ray crystallography.Refinement of atomic models in high resolution EM reconstructions using Flex-EM and local assessment.Estimation of Uncertainties in the Global Distance Test (GDT_TS) for CASP Models.A New Method for Determining Structure Ensemble: Application to a RNA Binding Di-Domain Protein.Time, space, and disorder in the expanding proteome universe.Predicting X-ray diffuse scattering from translation-libration-screw structural ensembles.Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in macromolecular structure determination.Deriving Structural Information from Experimentally Measured Data on Biomolecules.Understanding HIV-1 protease autoprocessing for novel therapeutic development.Flexible torsion-angle noncrystallographic symmetry restraints for improved macromolecular structure refinement.Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complexDiffuse X-ray scattering to model protein motionsImproved crystallographic structures using extensive combinatorial refinementDNA conformational transitions inferred from re-evaluation of m|Fo| - D|Fc| electron-density maps.TLS from fundamentals to practice.Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticityAn allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein.Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering.Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 Å resolution.The first step of peptide selection in antigen presentation by MHC class I molecules.Combining experiments and simulations using the maximum entropy principle.
P2860
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P2860
Modelling dynamics in protein crystal structures by ensemble refinement
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Modelling dynamics in protein crystal structures by ensemble refinement
@ast
Modelling dynamics in protein crystal structures by ensemble refinement
@en
type
label
Modelling dynamics in protein crystal structures by ensemble refinement
@ast
Modelling dynamics in protein crystal structures by ensemble refinement
@en
prefLabel
Modelling dynamics in protein crystal structures by ensemble refinement
@ast
Modelling dynamics in protein crystal structures by ensemble refinement
@en
P2093
P2860
P356
P1433
P1476
Modelling dynamics in protein crystal structures by ensemble refinement
@en
P2093
B Tom Burnley
Pavel V Afonine
P2860
P304
P356
10.7554/ELIFE.00311
P407
P577
2012-12-18T00:00:00Z