The mechanism of inhibition of the cyclin-dependent kinase-2 as revealed by the molecular dynamics study on the complex CDK2 with the peptide substrate HHASPRK
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Mechanism of p27 Unfolding for CDK2 Reactivation.Molecular basis of differential selectivity of cyclobutyl-substituted imidazole inhibitors against CDKs: insights for rational drug designTyrosine phosphorylation allows integration of multiple signaling inputs by IKKβPrediction of the binding mode between GSK3β and a peptide derived from GSKIP using molecular dynamics simulation.Determining the Functions of HIV-1 Tat and a Second Magnesium Ion in the CDK9/Cyclin T1 Complex: A Molecular Dynamics Simulation Study.Functional flexibility of human cyclin-dependent kinase-2 and its evolutionary conservation.Palbociclib can overcome mutations in cyclin dependent kinase 6 that break hydrogen bonds between the drug and the protein.Atrial natriuretic factor receptor guanylate cyclase, ANF-RGC, transduces two independent signals, ANF and Ca(2+).A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding.Ensemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone.How calcium inhibits the magnesium-dependent kinase gsk3β: a molecular simulation study.Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics.Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms.Mechanism of kinase inactivation and nonbinding of FRATide to GSK3β due to K85M mutation: molecular dynamics simulation and normal mode analysis.The effect of Li+ on GSK-3 inhibition: molecular dynamics simulation.Biomacromolecular Fragments and Patterns
P2860
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P2860
The mechanism of inhibition of the cyclin-dependent kinase-2 as revealed by the molecular dynamics study on the complex CDK2 with the peptide substrate HHASPRK
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2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
The mechanism of inhibition of ...... the peptide substrate HHASPRK
@ast
The mechanism of inhibition of ...... the peptide substrate HHASPRK
@en
type
label
The mechanism of inhibition of ...... the peptide substrate HHASPRK
@ast
The mechanism of inhibition of ...... the peptide substrate HHASPRK
@en
prefLabel
The mechanism of inhibition of ...... the peptide substrate HHASPRK
@ast
The mechanism of inhibition of ...... the peptide substrate HHASPRK
@en
P2860
P356
P1433
P1476
The mechanism of inhibition of ...... the peptide substrate HHASPRK
@en
P2093
Iveta Bártová
Zdenek Kríz
P2860
P304
P356
10.1110/PS.04959705
P577
2005-01-04T00:00:00Z