Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
about
The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancerFluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug ResponseAnalysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastomaInsight into the cooperative DNA binding of the O⁶-alkylguanine DNA alkyltransferase.Integrating Epigenomics into Pharmacogenomic StudiesHeritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.Cooperative cluster formation, DNA bending and base-flipping by O6-alkylguanine-DNA alkyltransferase.Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.S-alkylthiolation of O6-methylguanine-DNA-methyltransferase (MGMT) to sensitize cancer cells to anticancer therapy.Therapeutic potential of drugs to modulate DNA repair in cancer.Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.Inhibiting the DNA damage response as a therapeutic manoeuvre in cancer.Cell-centric view of apoptosis and apoptotic cell death-inducing antitumoral strategiesDNA repair proteins as molecular targets for cancer therapeutics.Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implicationsResistance gene expression determines the in vitro chemosensitivity of non-small cell lung cancer (NSCLC)Use of cell lines in the investigation of pharmacogenetic loci.Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Translating cancer research by synthetic biology.Towards tailored therapy of glioblastoma multiforme.DNA repair by reversal of DNA damage.Interactions of human O6-alkylguanine-DNA alkyltransferase (AGT) with short single-stranded DNAs.Interactions of human O(6)-alkylguanine-DNA alkyltransferase (AGT) with short double-stranded DNAsOptimizing glioblastoma temozolomide chemotherapy employing lentiviral-based anti-MGMT shRNA technologyHeterogeneity of human glioblastoma: glutathione-S-transferase and methylguanine-methyltransferase.Activity and regulation of archaeal DNA alkyltransferase: conserved protein involved in repair of DNA alkylation damage.Histone Methylation by Temozolomide; A Classic DNA Methylating Anticancer Drug.Noncoding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics.The Development of a Nano-based Approach to Alleviate Cisplatin-Induced Ototoxicity.
P2860
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P2860
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
@ast
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
@en
type
label
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
@ast
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
@en
prefLabel
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
@ast
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
@en
P1476
Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
@en
P2093
M Eileen Dolan
Maria Chidiamara Njoku
P304
P356
10.1016/J.CTRV.2006.03.004
P50
P577
2006-05-15T00:00:00Z