A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis - Wikidata - wikimedia - TriplyDB

A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis

A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis

http://www.wikidata.org/entity/Q36478058

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Eukaryotic DNA polymerase ζ Def1 promotes the degradation of Pol3 for polymerase exchange to occur during DNA-damage--induced mutagenesis in Saccharomyces cerevisiae.Genetic instability in budding and fission yeast-sources and mechanisms The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability A novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiae Ribonucleotide incorporation by yeast DNA polymerase ζ.Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins.An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε.The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.The C-terminal domain of the DNA polymerase catalytic subunit regulates the primase and polymerase activities of the human DNA polymerase α-primase complex Error-prone replication bypass of the primary aflatoxin B1 DNA adduct, AFB1-N7-Gua Translesion DNA polymerases Rescue from replication stress during mitosis.RPA coordinates DNA end resection and prevents formation of DNA hairpins.The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ.REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ FF483-484 motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage tolerance Crosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistance Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress.Loss of Pol32 in Drosophila melanogaster causes chromosome instability and suppresses variegation.Exo1 phosphorylation status controls the hydroxyurea sensitivity of cells lacking the Pol32 subunit of DNA polymerases delta and zeta Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit.Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements.The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells.PCNA is efficiently loaded on the DNA recombination intermediate to modulate polymerase δ, η, and ζ activities.Proficient Replication of the Yeast Genome by a Viral DNA Polymerase Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis.Oxidative DNA damage stalls the human mitochondrial replisome DNA-damage tolerance mediated by PCNA*Ub fusions in human cells is dependent on Rev1 but not Polη.Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ.The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis.Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Break-induced telomere synthesis underlies alternative telomere maintenance.In vivo evidence for translesion synthesis by the replicative DNA polymerase δ.Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases.Translesion DNA polymerases in eukaryotes: what makes them tick?

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P2860

A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis

http://www.wikidata.org/entity/Q36478058

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

A four-subunit DNA polymerase ...... for PCNA-mediated mutagenesis

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A four-subunit DNA polymerase ...... for PCNA-mediated mutagenesis

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type

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A four-subunit DNA polymerase ...... for PCNA-mediated mutagenesis

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A four-subunit DNA polymerase ...... for PCNA-mediated mutagenesis

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prefLabel

A four-subunit DNA polymerase ...... for PCNA-mediated mutagenesis

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A four-subunit DNA polymerase ...... for PCNA-mediated mutagenesis

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Nucleic Acids Research

P1476

A four-subunit DNA polymerase ...... for PCNA-mediated mutagenesis

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P2093

Alena V Makarova

http://www.w3.org/2001/XMLSchema#string

Joseph L Stodola

http://www.w3.org/2001/XMLSchema#string

Peter M Burgers

http://www.w3.org/2001/XMLSchema#string

P2860

Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7

Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1

A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta

X-ray structure of the complex of regulatory subunits of human DNA polymerase delta

3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage.

Mutants of yeast defective in mutation induced by ultraviolet light

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

Thymine-thymine dimer bypass by yeast DNA polymerase zeta.

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11618-11626

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scholarly article

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10.1093/NAR/GKS948

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22

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40

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2012-10-12T00:00:00Z

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232248289

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23066099

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3526297

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