Somatic cell nuclear transfer efficiency: how can it be improved through nuclear remodeling and reprogramming?
about
Emerging applications of sperm, embryo and somatic cell cryopreservation in maintenance, relocation and rederivation of swine geneticsPositive correlation between the efficiency of induced pluripotent stem cells and the development rate of nuclear transfer embryos when the same porcine embryonic fibroblast lines are used as donor cells.Uncoupled embryonic and extra-embryonic tissues compromise blastocyst development after somatic cell nuclear transfer.Completion of the swine genome will simplify the production of swine as a large animal biomedical model.Trichostatin A-mediated epigenetic transformation of adult bone marrow-derived mesenchymal stem cells biases the in vitro developmental capability, quality, and pluripotency extent of porcine cloned embryos.Discovery of porcine maternal factors related to nuclear reprogramming and early embryo development by proteomic analysis.Epigenetic modification with trichostatin A does not correct specific errors of somatic cell nuclear transfer at the transcriptomic level; highlighting the non-random nature of oocyte-mediated reprogramming errors.Transcriptome Analysis of Pig In Vivo, In Vitro-Fertilized, and Nuclear Transfer Blastocyst-Stage Embryos Treated with Histone Deacetylase Inhibitors Postfusion and Activation Reveals Changes in the Lysosomal PathwayThe influence of DNA sequence on epigenome-induced pathologies.Effects of combined treatment of MG132 and scriptaid on early and term development of porcine somatic cell nuclear transfer embryosXenopus egg extract treatment reduced global DNA methylation of donor cells and enhanced somatic cell nuclear transfer embryo development in pigs.Effects of donor fibroblast cell type and transferred cloned embryo number on the efficiency of pig cloning.Bone marrow mesenchymal stem cells are an attractive donor cell type for production of cloned pigs as well as genetically modified cloned pigs by somatic cell nuclear transfer.Identification and characterization of an oocyte factor required for porcine nuclear reprogrammingA simplified one-step nuclear transfer procedure alters the gene expression patterns and developmental potential of cloned porcine embryos.Epigenetic reprogramming, gene expression and in vitro development of porcine SCNT embryos are significantly improved by a histone deacetylase inhibitor--m-carboxycinnamic acid bishydroxamide (CBHA).Stem cell therapy: an exercise in patience and prudence.MicroRNA-148a overexpression improves the early development of porcine somatic cell nuclear transfer embryos.Pharmacologic treatment of donor cells induced to have a Warburg Effect-like metabolism does not alter embryonic development in vitro or survival during early gestation when used in somatic cell nuclear transfer in pigs.Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs.Epigenetic modification of fetal fibroblasts improves developmental competency and gene expression in porcine cloned embryos.Successful cloning of an adult breeding boar from the novel Chinese Guike No. 1 swine specialized strain.Generation of AQP2-Cre transgenic mini-pigs specifically expressing Cre recombinase in kidney collecting duct cells.Pathways to de-extinction: how close can we get to resurrection of an extinct species?Porcine Fetal-Derived Fibroblasts Alter Gene Expression and Mitochondria to Compensate for Hypoxic Stress During Culture
P2860
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P2860
Somatic cell nuclear transfer efficiency: how can it be improved through nuclear remodeling and reprogramming?
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Somatic cell nuclear transfer ...... remodeling and reprogramming?
@ast
Somatic cell nuclear transfer ...... remodeling and reprogramming?
@en
type
label
Somatic cell nuclear transfer ...... remodeling and reprogramming?
@ast
Somatic cell nuclear transfer ...... remodeling and reprogramming?
@en
prefLabel
Somatic cell nuclear transfer ...... remodeling and reprogramming?
@ast
Somatic cell nuclear transfer ...... remodeling and reprogramming?
@en
P2860
P356
P1476
Somatic cell nuclear transfer ...... remodeling and reprogramming?
@en
P2093
Kristin M Whitworth
P2860
P304
P356
10.1002/MRD.21242
P577
2010-10-07T00:00:00Z