Protein kinase C delta is required for survival of cells expressing activated p21RAS - Wikidata - wikimedia - TriplyDB

Protein kinase C delta is required for survival of cells expressing activated p21RAS

Protein kinase C delta is required for survival of cells expressing activated p21RAS

http://www.wikidata.org/entity/Q36480153

about

K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function Targeting the RAS oncogene.Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway PKCδ-dependent signaling mediates ethambutol-induced toxic effects on human retinal pigment cells.Protein kinase Cδ is a therapeutic target in malignant melanoma with NRAS mutation.Differential sensitization of different prostate cancer cells to apoptosis.Protein kinase C-δ inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo Protein kinase C δ is a downstream effector of oncogenic K-ras in lung tumors.Protein kinase Cδ inactivation inhibits cellular proliferation and decreases survival in human neuroendocrine tumors.Phosphorylation of protein kinase Cdelta on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: role in the apoptotic effect of etoposide PKCdelta survival signaling in cells containing an activated p21Ras protein requires PDK1.Anti-apoptotic effects of protein kinase C-delta and c-fos in cisplatin-treated thyroid cells.Protein kinase Cdelta supports survival of MDA-MB-231 breast cancer cells by suppressing the ERK1/2 pathway.Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin.Phosphoproteomic analysis reveals the importance of kinase regulation during orbivirus infection.Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells.Multifunctional roles of PKCδ: Opportunities for targeted therapy in human disease Roles of PKC isoforms in the induction of apoptosis elicited by aberrant Ras.PI3K Acts in synergy with loss of PKC to elicit apoptosis via the UPR.Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C.Co-dependency of PKCδ and K-Ras: inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer.Synthetic Lethality Induced by Loss of PKC δ and Mutated Ras Chromium IV exposure, via Src/Ras signaling, promotes cell transformation.Protein Kinase Cδ Suppresses Autophagy to Induce Kidney Cell Apoptosis in Cisplatin Nephrotoxicity.Interlukin-18 Is a Pivot Regulatory Factor on Matrix Metalloproteinase-13 Expression and Brain Astrocytic Migration.

P2860

Q24298001-6B2D7FCC-4D4B-44B3-ABFE-129E4F474492 Q27687198-BEC2AD9A-53FA-4500-8FCB-68CAF9A7E594 Q28572961-1DAB8921-E140-4DF7-9626-F71BE8DE6755 Q33954285-4E3E0114-5423-429E-9795-924113345609 Q34159519-3B4D56CE-6936-4F75-B07E-AB2B4D4202A2 Q34370353-9490C8E4-F14F-4FCF-B3AE-56D27D9FBF9E Q35094509-84655D13-18CB-400F-B254-C482878BACE3 Q35733900-F9C7CC42-EAE1-4685-BA20-230DCFA5666A Q36480150-16550F83-65F5-4B9C-A463-9971E47DDE15 Q36719264-07ABBF56-B309-434C-9858-A7501522508A Q37101645-3A0FF92C-A43C-434D-B44B-069242222114 Q37230815-9B372B20-E769-4199-B5F6-870B1E31AE10 Q37446199-08B88C81-F520-404C-8100-518897191B8C Q38200047-20FA64D5-744D-4DA6-913D-C933191D89B6 Q38603209-AC34F155-4DEE-4BEE-826D-46CF61C1E701 Q38834064-B99C4C06-200B-41EB-BFA7-3D3E2027385A Q38834586-4EEEA9D5-AB95-4BEB-8DED-004B382945A4 Q39786241-C5F85423-3EB3-496E-A299-6F03CB781863 Q39880033-D72AE48B-1088-42CA-94BC-77F8340D4E88 Q42055537-1F17E721-57BF-4070-AEE4-E88C78C0598B Q42338790-F0CBFF74-085A-402B-B1DC-50D9A33919C4 Q42398004-D6173960-6AF5-4E36-92C9-766815236604 Q46415206-916C7CBD-1026-4674-94DB-60504AE8FA6E Q48037609-B2564271-948B-4D43-BC91-ADC0EDF6CD0A Q48451367-5EF95590-F3CE-4914-A1B7-D83DCF4CC459

P2860

Protein kinase C delta is required for survival of cells expressing activated p21RAS

http://www.wikidata.org/entity/Q36480153

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh

2007年學術文章

@zh-hant

name

Protein kinase C delta is required for survival of cells expressing activated p21RAS

@ast

Protein kinase C delta is required for survival of cells expressing activated p21RAS

@en

type

label

Protein kinase C delta is required for survival of cells expressing activated p21RAS

@ast

Protein kinase C delta is required for survival of cells expressing activated p21RAS

@en

prefLabel

Protein kinase C delta is required for survival of cells expressing activated p21RAS

@ast

Protein kinase C delta is required for survival of cells expressing activated p21RAS

@en

P1433

Q36480153-9D45EFBF-8B2D-48B0-AF48-CEC31AAEB3B8

P1476

Q36480153-D69F1292-29A3-404D-AC02-0C4EB2AB40FC

P2093

Q36480153-339E6099-57D9-4294-A8E6-76FECCC26318

Q36480153-41178C9E-E61A-45CE-95D4-F5034917CE35

Q36480153-EAC1E3CC-B27D-4C99-ABAA-BAB519C2D355

P2860

Q36480153-038B6622-09D8-434B-AB2C-F1E33B75AA05

Q36480153-0A514C37-162D-4CBC-8FF7-8676C004E4FB

Q36480153-108C3C07-EC06-4EE6-85F5-CBA85568E74F

Q36480153-14D8211F-9991-46CD-83D1-76CEA4998D65

Q36480153-1551F8CE-BD41-4EDF-921A-9FC7B42A7BBD

Q36480153-1DE65B33-0365-42CF-88F3-1CE0AF21464F

Q36480153-21E68D16-65CF-45F8-B90D-28D700450C86

Q36480153-263732EA-7C74-4185-9CB6-C8C33BA3B64E

Q36480153-2977827A-29FB-4B0E-A2CD-5823C11CB314

Q36480153-2F46657B-19DD-4C44-B488-0E83088E0640

P304

Q36480153-8A408232-6605-42A7-A6D8-F9D1E636C768

P31

Q36480153-290D71FD-1C0C-40B1-946E-E488ADC5D4F6

P356

Q36480153-7920CC58-0D6E-444E-9C11-E1369FEBF017

P407

Q36480153-DADA71A4-F8E9-4293-9508-3DBF2A08289D

P433

Q36480153-195D09B8-9824-4F0F-B793-AF271432426B

P478

Q36480153-C8A88B98-1450-44CC-A594-E56EE4191409

P577

Q36480153-E0FEB460-3B51-4D1B-8F39-AA5B9269A6ED

P698

Q36480153-28A67B29-5EEE-496C-94C6-0A780EFD0270

P932

Q36480153-C55BB302-E054-42F0-A85B-60E6C7965700

P356

P1433

Journal of Biological Chemistry

P1476

Protein kinase C delta is required for survival of cells expressing activated p21RAS

@en

P2093

Douglas V Faller

http://www.w3.org/2001/XMLSchema#string

Lora W Forman

http://www.w3.org/2001/XMLSchema#string

Shuhua Xia

http://www.w3.org/2001/XMLSchema#string

P2860

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization.

Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9

Roles of tyrosine phosphorylation and cleavage of protein kinase Cdelta in its protective effect against tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Targeting RAS signalling pathways in cancer therapy

Regulation of cell apoptosis by protein kinase c delta

Identification of a novel Ras-regulated proapoptotic pathway

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

P304

13199-13210

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M610225200

http://www.w3.org/2001/XMLSchema#string

P407

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

282

http://www.w3.org/2001/XMLSchema#string

P577

2007-03-08T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17350960

http://www.w3.org/2001/XMLSchema#string

P932

3527128

http://www.w3.org/2001/XMLSchema#string