Kaposi's sarcoma-associated herpesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing.
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Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral ReplicationKaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways.Caspase-7 cleavage of Kaposi sarcoma-associated herpesvirus ORF57 confers a cellular function against viral lytic gene expression.The suppression of apoptosis by α-herpesvirus.An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export.Requirement of UAP56, URH49, RBM15, and OTT3 in the expression of Kaposi sarcoma-associated herpesvirus ORF57.Attenuation of the suppressive activity of cellular splicing factor SRSF3 by Kaposi sarcoma-associated herpesvirus ORF57 protein is required for RNA splicingKaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.Kaposi's sarcoma-associated herpesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppressionIdentification of the physiological gene targets of the essential lytic replicative Kaposi's sarcoma-associated herpesvirus ORF57 proteinMechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and ReactivationStability of structured Kaposi's sarcoma-associated herpesvirus ORF57 protein is regulated by protein phosphorylation and homodimerization.KSHV ORF57, a protein of many facesA novel mechanism inducing genome instability in Kaposi's sarcoma-associated herpesvirus infected cells.Stability of a long noncoding viral RNA depends on a 9-nt core element at the RNA 5' end to interact with viral ORF57 and cellular PABPC1.HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma-associated herpesvirus ORF57 protein and host pre-mRNA metabolismStructure of the C-Terminal Domain of the Multifunctional ICP27 Protein from Herpes Simplex Virus 1Binding of cellular export factor REF/Aly by Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 protein is not required for efficient KSHV lytic replication.Kaposi's sarcoma-associated herpesvirus ORF57 is not a bona fide export factor.Kaposi's sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation.Interplay between polyadenylate-binding protein 1 and Kaposi's sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.Analysis of influenza B Virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domainsKaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.Cell-based screening assay for antiviral compounds targeting the ability of herpesvirus posttranscriptional regulatory proteins to stabilize viral mRNAs.Herpesvirus protein ICP27 switches PML isoform by altering mRNA splicing.The many roles of the highly interactive HSV protein ICP27, a key regulator of infection.KSHV Rta Promoter Specification and Viral Reactivation.The Kaposi's Sarcoma-Associated Herpesvirus ORF57 Protein and Its Multiple Roles in mRNA Biogenesis.Kaposi's sarcoma-associated herpesvirus ORF57 protein: exploiting all stages of viral mRNA processing.Mutation of a C-terminal motif affects Kaposi's sarcoma-associated herpesvirus ORF57 RNA binding, nuclear trafficking, and multimerization.Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity.Nucleolar disruption impairs Kaposi's sarcoma-associated herpesvirus ORF57-mediated nuclear export of intronless viral mRNAs.ORF57 overcomes the detrimental sequence bias of Kaposi's sarcoma-associated herpesvirus lytic genes.Evidence for a Mesothelial Origin of Body Cavity Effusion Lymphomas.CLIP-seq to Identify KSHV ORF57-Binding RNA in Host B Cells.KSHV and the Role of Notch Receptor Dysregulation in Disease Progression.KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation.
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P2860
Kaposi's sarcoma-associated herpesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
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name
Kaposi's sarcoma-associated he ...... ceosome-mediated RNA splicing.
@ast
Kaposi's sarcoma-associated he ...... ceosome-mediated RNA splicing.
@en
type
label
Kaposi's sarcoma-associated he ...... ceosome-mediated RNA splicing.
@ast
Kaposi's sarcoma-associated he ...... ceosome-mediated RNA splicing.
@en
prefLabel
Kaposi's sarcoma-associated he ...... ceosome-mediated RNA splicing.
@ast
Kaposi's sarcoma-associated he ...... ceosome-mediated RNA splicing.
@en
P2093
P2860
P356
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P1476
Kaposi's sarcoma-associated he ...... ceosome-mediated RNA splicing.
@en
P2093
Eric Allemand
Koji Yamanegi
Michael Kruhlak
Vladimir Majerciak
Zhi-Ming Zheng
P2860
P304
P356
10.1128/JVI.01856-07
P407
P577
2008-01-09T00:00:00Z