Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. - Wikidata - wikimedia - TriplyDB

Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.

Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.

http://www.wikidata.org/entity/Q36485293

about

Dinosaurs and ancient civilizations: reflections on the treatment of cancer DNA demethylation and invasive cancer: implications for therapeutics Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications Promoter methylation of aminopeptidase N/CD13 in malignant melanoma.Neoplasia: the second decade.Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene.Versatile role of heparanase in inflammation DNA hypomethylation in cancer cells.Epigenetic silencing of CXCR4 promotes loss of cell adhesion in cervical cancer.S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer.Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness Curcumin modulates DNA methylation in colorectal cancer cells.CHST11 gene expression and DNA methylation in breast cancer DNA methylation of heparanase promoter influences its expression and associated with the progression of human breast cancer Epigenetic mechanisms involved in developmental nutritional programming.S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications DNA Methylation and Flavonoids in Genitourinary Cancers.The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma.DNA methylation signatures for breast cancer classification and prognosis Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.Frequent S100A4 Expression with Unique Splicing Pattern in Gastric Cancers: A Hypomethylation Event Paralleled with E-cadherin Reduction and Wnt Activation Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia.DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis The War on Cancer rages on.Epigenetic therapeutics in autoimmune disease.Epigenetic alterations involved in cancer stem cell reprogramming.Heparanase in inflammation and inflammation-associated cancer.DNA methylation and apoptosis resistance in cancer cells Targeted therapy of epigenomic regulatory mechanisms controlling the epithelial to mesenchymal transition during tumor progression.A novel epigenetic mechanism regulating hyaluronan production in pancreatic cancer cells.Regulation of the ITGA2 gene by epigenetic mechanisms in prostate cancer.Pharmacological methyl group donors block skeletal metastasis in vitro and in vivo.Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease.Evaluating cell migration in vitro by the method based on cell patterning within microfluidic channels.DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo.Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine.Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors.Epigenetic regulation of miR-196b expression in gastric cancer.Osteoblasts modulate Ca2+ signaling in bone-metastatic prostate and breast cancer cells.

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P2860

Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.

http://www.wikidata.org/entity/Q36485293

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Alexander Unterberger

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Bushra Ateeq

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Moshe Szyf

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Shafaat A Rabbani

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P2860

Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation

Transforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer.

Targeted therapy against Bcl-2-related proteins in breast cancer cells

A gene-expression signature as a predictor of survival in breast cancer

New functions for the matrix metalloproteinases in cancer progression

Breast cancer metastasis: markers and models

Urokinase plasminogen activator: a prognostic marker in multiple types of cancer.

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development.

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer.

Towards a pharmacology of DNA methylation.

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266-278

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10.1593/NEO.07947

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3

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10

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18320071

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DNA methylation

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2259455

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