about
Customizing the genome as therapy for the β-hemoglobinopathiesOxidative stress in β-thalassaemia and sickle cell diseaseGenomic approaches to identifying targets for treating β hemoglobinopathiesTranslational control by heme-regulated eIF2α kinase during erythropoiesisAnemia: progress in molecular mechanisms and therapiesErythro-megakaryocytic transcription factors associated with hereditary anemiaHemoglobin variants: biochemical properties and clinical correlatesBCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.KLF1 mutations are relatively more common in a thalassemia endemic region and ameliorate the severity of β-thalassemiaLIN28A expression reduces sickling of cultured human erythrocytes.Gene therapy for hemoglobinopathies: the state of the field and the future.Induction of fetal hemoglobin through enhanced translation efficiency of γ-globin mRNAErythropoiesis: development and differentiation.In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors.Distinctive patterns of evolution of the δ-globin gene (HBD) in primatesInhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.The hemoglobin E thalassemias.Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting.Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.Pathophysiology and Clinical Manifestations of the β-Thalassemias.Advances in understanding erythropoiesis: evolving perspectivesDevelopment of filter paper hemoglobin A1c assay applicable to newborn screening.Eukaryotic initiation factor 2α phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanismTranscriptional mechanisms underlying hemoglobin synthesis.Development of gene therapy for blood disorders: an update.Establishing a hematopoietic genetic network through locus-specific integration of chromatin regulators.Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.Classification of the disorders of hemoglobinConcise review: stem cell-based approaches to red blood cell production for transfusion.Management of non-transfusion-dependent thalassemia: a practical guide.Triterpenoid inducers of Nrf2 signaling as potential therapeutic agents in sickle cell disease: a review.The Influence of Polymorphisms in Disease Severity in β-Thalassemia.HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers.Society for Pediatric Research 2015 Young Investigator Award: genetics of human hematopoiesis-what patients can teach us about blood cell production.Developmentally-faithful and effective human erythropoiesis in immunodeficient and Kit mutant mice.Gamma reactivation using the spongy effect of KLF1-binding site sequence: an approach in gene therapy for beta-thalassemia.The expanding role of the Ehmt2/G9a complex in neurodevelopment.Minireview: Genetic basis of heterogeneity and severity in sickle cell disease.Development of autologous blood cell therapies.Emerging cellular and gene therapies for congenital anemias.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
The switch from fetal to adult hemoglobin
@ast
The switch from fetal to adult hemoglobin
@en
type
label
The switch from fetal to adult hemoglobin
@ast
The switch from fetal to adult hemoglobin
@en
prefLabel
The switch from fetal to adult hemoglobin
@ast
The switch from fetal to adult hemoglobin
@en
P2860
P1476
The switch from fetal to adult hemoglobin
@en
P2093
Stuart H Orkin
Vijay G Sankaran
P2860
P304
P356
10.1101/CSHPERSPECT.A011643
P577
2013-01-01T00:00:00Z