"Optical patch-clamping": single-channel recording by imaging Ca2+ flux through individual muscle acetylcholine receptor channels
about
In-depth activation of channelrhodopsin 2-sensitized excitable cells with high spatial resolution using two-photon excitation with a near-infrared laser microbeamImaging single-channel calcium microdomainsTRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarizationCardiac optogeneticsSubplasmalemmal Ca(2+) measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretionRecording single-channel activity of inositol trisphosphate receptors in intact cells with a microscope, not a patch clamp.Imaging the quantal substructure of single IP3R channel activity during Ca2+ puffs in intact mammalian cells.Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells.Spatiotemporal resolution of mast cell granule exocytosis reveals correlation with Ca2+ wave initiationTracking transmitter-gated P2X cation channel activation in vitro and in vivoLabel-free optical detection of biomolecular translocation through nanopore arrays.A comparison of fluorescent Ca²⁺ indicators for imaging local Ca²⁺ signals in cultured cells.Quantifying calcium fluxes underlying calcium puffs in Xenopus laevis oocytes.Calcium signaling and amyloid toxicity in Alzheimer disease.Superresolution localization of single functional IP3R channels utilizing Ca2+ flux as a readoutCalcium Green FlAsH as a genetically targeted small-molecule calcium indicator.Natural inequalities: why some L-type Ca2+ channels work harder than othersTermination of calcium puffs and coupled closings of inositol trisphosphate receptor channels.An algorithm for automated detection, localization and measurement of local calcium signals from camera-based imagingActivity and Ca²⁺ regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons.Fluorescence fluctuations and equivalence classes of Ca²⁺ imaging experiments.Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states.Single-channel Ca(2+) imaging implicates Aβ1-42 amyloid pores in Alzheimer's disease pathologyAnalyzing and Modeling the Kinetics of Amyloid Beta Pores Associated with Alzheimer's Disease Pathology.Genetically targeted single-channel optical recording reveals multiple Orai1 gating states and oscillations in calcium influx.Plasmalemmal Ca2+ signaling in arterial smooth muscle: it's elementary!Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle.Local regulation of L-type Ca²⁺ channel sparklets in arterial smooth muscleCaV1.2 sparklets in heart and vascular smooth muscleCytosolic [Ca2+] regulation of InsP3-evoked puffs.Localization of puff sites adjacent to the plasma membrane: functional and spatial characterization of Ca2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP3.cADPR stimulates SERCA activity in Xenopus oocytesSingle-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptorsIon trapping with fast-response ion-selective microelectrodes enhances detection of extracellular ion channel gradients.Factors determining the recruitment of inositol trisphosphate receptor channels during calcium puffs.Molecular and biophysical mechanisms of Ca2+ sparklets in smooth muscleThe structural basis of function in Cys-loop receptors.Strategies for the real-time detection of Ca2+ channel events of single cells: recent advances and new possibilities.Patch-clamp electrophysiology of intracellular Ca2+ channels.Communication of Ca(2+) signals via tunneling membrane nanotubes is mediated by transmission of inositol trisphosphate through gap junctions.
P2860
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P2860
"Optical patch-clamping": single-channel recording by imaging Ca2+ flux through individual muscle acetylcholine receptor channels
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
"Optical patch-clamping": sing ...... cetylcholine receptor channels
@ast
"Optical patch-clamping": sing ...... cetylcholine receptor channels
@en
type
label
"Optical patch-clamping": sing ...... cetylcholine receptor channels
@ast
"Optical patch-clamping": sing ...... cetylcholine receptor channels
@en
prefLabel
"Optical patch-clamping": sing ...... cetylcholine receptor channels
@ast
"Optical patch-clamping": sing ...... cetylcholine receptor channels
@en
P2860
P356
P1476
"Optical patch-clamping": sing ...... cetylcholine receptor channels
@en
P2093
Angelo Demuro
Ian Parker
P2860
P304
P356
10.1085/JGP.200509331
P577
2005-08-15T00:00:00Z