CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling. - Wikidata - wikimedia - TriplyDB

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

http://www.wikidata.org/entity/Q36497247

about

Dual effect of oxidative stress on leukemia cancer induction and treatment Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondria The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML.G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol.Palbociclib can overcome mutations in cyclin dependent kinase 6 that break hydrogen bonds between the drug and the protein.Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation through MicroRNA and Gene Targets.Role of the reprogramming factor KLF4 in blood formation.KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis.KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis.Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway.Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia.Anakoinosis: Communicative Reprogramming of Tumor Systems - for Rescuing from Chemorefractory Neoplasia Targeting self-renewal pathways in myeloid malignancies.Biomodulatory therapy induces complete molecular remission in chemorefractory acute myeloid leukemia.Deregulation of the CDX2-KLF4 axis in acute myeloid leukemia and colon cancer.G0S2--a new player in leukemia.Reduction in Cell Viability and in Homeobox Protein Levels Following in Vitro Exposure to δ-tocopherol in Acute Myeloid Leukemia.Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche.DNA-Methyltransferase 1 Induces Dedifferentiation of Pancreatic Cancer Cells through Silencing of Krüppel-Like Factor 4 Expression.

P2860

Q26866544-87565191-02BB-40DF-B406-348F14F473B2 Q34310186-620947D9-6F96-4E36-9CE8-0E0E75C7F412 Q35935293-550D925C-FF42-41AA-B8EE-C286D97A7BBD Q36547690-1DD1EA0F-BF0B-49DB-96B4-DF24EF3CDB35 Q37625352-323BD49D-6B14-4FE7-8B18-F0832A0FDCEE Q37723172-C668BA82-30F3-45A0-B23E-C2F0BA041AFE Q38384041-EB4E240D-CF9A-48CB-B58D-9F8D92F19F69 Q38747777-EBBC5F16-B643-427A-BC55-D36344E494CB Q38786245-84622058-8E33-4FC6-B2D9-6A4CC68DB89B Q38793918-56494293-0BE8-460F-8647-E8C47A2F2509 Q39166310-C066C040-05FB-4D86-99C3-E2D40F5625A5 Q39289226-D07F4859-B3C0-46EF-A010-8944A4CF76CC Q40640442-D78118CE-52FB-4F50-9402-77DB3A3375F1 Q41104001-DB318042-62F2-4687-9342-023F8EDE156C Q42550846-79E66C0B-923E-4470-A950-0D02631BC5A8 Q43090143-51191265-4B0D-48D5-8AAD-4B9AC0B67E99 Q43198956-25D57DB7-1A77-45B1-8382-5DBF961032D9 Q44432135-9813AD05-81F5-47E8-A3DC-9011E1010D10 Q47648907-96CAF529-53A8-4C66-B472-A43273F18C66 Q50918212-A22E2A5B-725F-4F2B-8016-BD6AC288E68A

P2860

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

http://www.wikidata.org/entity/Q36497247

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

@ast

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

@en

type

label

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

@ast

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

@en

prefLabel

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

@ast

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

@en

P1433

Q36497247-CACF4465-6BCB-4FBA-A9E6-DDBC424AF08D

P1476

Q36497247-0B9349B0-98A3-4EDB-B27C-E7312DE8C917

P2093

Q36497247-1B81B47D-5165-4C5D-8724-C638DB3E1575

Q36497247-26FD1C35-8078-4D5C-847A-03DA6E1798DF

Q36497247-4DCDF085-31A6-4E97-A08B-A5813EB92227

Q36497247-525D8553-5ED9-4EE0-A354-B766D8935C77

Q36497247-536A9B6F-73A9-4935-A5DA-D0622D7A853A

Q36497247-5A0D3B5A-61FC-4502-8D94-F79F7FC76960

Q36497247-91023F7A-7E4B-4AD2-8C64-22ECD4141A8D

Q36497247-A545C23C-C5FF-4DC1-9ADE-924BAF553635

Q36497247-A5CBDC81-C5E9-4D60-9CBB-7C95E0E1F1B4

Q36497247-BFA62018-BEEC-4518-B670-331D11373F58

P2860

Q36497247-0A0E6787-7816-423E-8485-026031F0B5E1

Q36497247-0A8CE411-D520-48ED-8BEA-1323DB3A1F61

Q36497247-127B91ED-9DFD-4B00-A328-10759CFF90BC

Q36497247-1C110F88-58DF-4B7F-8D27-9F5C13F7FE87

Q36497247-25535FDA-9C5E-4249-889B-E8762E453863

Q36497247-2557D406-23EF-4B27-B0C9-3E5D5C132050

Q36497247-258FD2DA-9258-4195-B9D1-B730D7B27430

Q36497247-2A0CB1F9-0695-4ED5-995F-4F44DAE40C6E

Q36497247-2D1A0E7B-521F-4986-8A90-4E9AC061ED97

Q36497247-305A3A8B-F8CC-4668-A318-068FEEC29C5C

P304

Q36497247-5C73756F-8AFF-4E48-8FCF-FEAFDE5C0439

P31

Q36497247-AA602779-2D86-40FD-95B8-7A7FAA2AA8B1

P356

Q36497247-D1900A5C-0296-48A8-8AC1-7721D55BD25C

P407

Q36497247-559D5932-581F-42AF-8362-E480FAD8DD41

P433

Q36497247-68FB14BA-B6BA-4BA8-8AE0-5A966A9AAAA1

P478

Q36497247-DBF89E90-ECFF-4797-B8B4-E1A5A4AC559E

P50

Q36497247-9B378985-0AFC-4AD1-AF42-6EBAFC0CA965

Q36497247-D3D64EAC-2CCF-4062-B6E9-9213C46F0ABC

P577

Q36497247-C45FD1AD-700C-4120-B56F-889AB5184625

P5875

Q36497247-68E364AD-9DF8-478A-85FA-FFE3D0065974

P698

Q36497247-12D0C693-ED26-408F-A09C-507183F3120C

P932

Q36497247-58B20E00-4DC2-41B6-BC0A-087932098469

P356

P1433

Journal of Clinical Investigation

P1476

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.

@en

P2093

Angela Garding

http://www.w3.org/2001/XMLSchema#string

Christina Miller

http://www.w3.org/2001/XMLSchema#string

Christine Ragu

http://www.w3.org/2001/XMLSchema#string

Christoph Plass

http://www.w3.org/2001/XMLSchema#string

Claudia Scholl

http://www.w3.org/2001/XMLSchema#string

Daniel Mertens

http://www.w3.org/2001/XMLSchema#string

Daniel Walcher

http://www.w3.org/2001/XMLSchema#string

Daniela Martin

http://www.w3.org/2001/XMLSchema#string

Katrin Faber

http://www.w3.org/2001/XMLSchema#string

Lars Bullinger

http://www.w3.org/2001/XMLSchema#string

P2860

Homeosis and intestinal tumours in Cdx2 mutant mice

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

Cdx2 is essential for axial elongation in mouse development

A homeodomain protein related to caudal regulates intestine-specific gene transcription

Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

The RUNX genes: gain or loss of function in cancer

TGFbeta in Cancer

P304

299-314

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI64745

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

123

http://www.w3.org/2001/XMLSchema#string

P50

Hartmut Döhner

Konstanze Döhner

P577

2012-12-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

233829049

http://www.w3.org/2001/XMLSchema#string

P698

23202735

http://www.w3.org/2001/XMLSchema#string

P932

3533294

http://www.w3.org/2001/XMLSchema#string