Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus - Wikidata - wikimedia - TriplyDB

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

http://www.wikidata.org/entity/Q36498051

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The conundrum of causality in tumor virology: the cases of KSHV and MCV Inflammatory cell distribution in primary merkel cell carcinoma.Palliative treatment for in-transit cutaneous metastases of Merkel cell carcinoma using surface-mold computer-optimized high-dose-rate brachytherapy.Milestones in the staging, classification, and biology of Merkel cell carcinoma Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus.A cornucopia of human polyomaviruses.Merkel cell polyomavirus and extrapulmonary small cell carcinoma.Different serologic behavior of MCPyV, TSPyV, HPyV6, HPyV7 and HPyV9 polyomaviruses found on the skin.Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.Prognostic value of immune cell infiltration, tertiary lymphoid structures and PD-L1 expression in Merkel cell carcinomas.The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice.The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma.Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation.Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model Multiple Primary Merkel Cell Carcinomas Presenting as Pruritic, Painful Lower Leg Tumors.Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression Combined squamous cell carcinoma and Merkel cell carcinoma of the vulva: Role of human papillomavirus and Merkel cell polyomavirus.Merkel cell polyomavirus large T antigen disrupts host genomic integrity and inhibits cellular proliferation.PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival.MicroRNA expression patterns related to merkel cell polyomavirus infection in human merkel cell carcinoma.Emerging and mechanism-based therapies for recurrent or metastatic Merkel cell carcinoma Human Merkel cell polyomavirus: virological background and clinical implications.Merkel cell carcinoma: is this a true carcinoma?Avelumab in patients with chemotherapy-refractory metastatic Merkel cell carcinoma: a multicentre, single-group, open-label, phase 2 trial.Neuroendocrine Merkel cell carcinoma is associated with mutations in key DNA repair, epigenetic and apoptosis pathways: a case-based study using targeted massively parallel sequencing Merkel cell carcinoma and Merkel cell polyomavirus: a systematic review and meta-analysis.Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival.Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA In Situ Hybridization Assay.ABCB5-Targeted Chemoresistance Reversal Inhibits Merkel Cell Carcinoma Growth.Serine 220 phosphorylation of the Merkel cell polyomavirus large T antigen crucially supports growth of Merkel cell carcinoma cells.Merkel Cell Carcinoma Therapeutic Update.T-cell responses to oncogenic merkel cell polyomavirus proteins distinguish patients with merkel cell carcinoma from healthy donors.Merkel cell polyomavirus infection and Merkel cell carcinoma.Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma Merkel cell carcinoma expresses vasculogenic mimicry: demonstration in patients and experimental manipulation in xenografts.Intraepidermal Merkel cell carcinoma with pagetoid Bowen's disease.RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.Merkel cell polyomavirus and Merkel cell carcinoma.Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting.

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Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

http://www.wikidata.org/entity/Q36498051

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2012年学术文章

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2012年學術文章

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name

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

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Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

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Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

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Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

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prefLabel

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

@ast

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

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Journal of Clinical Investigation

P1476

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

@en

P2093

Alejandro Martinez-Fernandez

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Alvaro C Laga

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Andrew DoRosario

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Dustin T Holloway

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Dylan J Cooper

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Jacek Wardzala

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James A DeCaprio

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Jessica J Scanlon

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Jingwei Cheng

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Justine A Barletta

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P2860

Cellular and viral factors regulating Merkel cell polyomavirus replication

Profiling critical cancer gene mutations in clinical tumor samples

Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

Clonal integration of a polyomavirus in human Merkel cell carcinoma

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

High throughput interrogation of somatic mutations in high grade serous cancer of the ovary

Hybrid capture and next-generation sequencing identify viral integration sites from formalin-fixed, paraffin-embedded tissue.

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4645-4653

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10.1172/JCI64116

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12

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122

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Andrew M Bellizzi

Subhashini Sadasivam

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2012-11-01T00:00:00Z

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23114601

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3533549

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