JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity
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RasGRP1 is required for human NK cell functionCell biological steps and checkpoints in accessing NK cell cytotoxicityProtein Kinase Inhibitors CK59 and CID755673 Alter Primary Human NK Cell Effector FunctionsRapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signalingBacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergyMifepristone increases the cytotoxicity of uterine natural killer cells by acting as a glucocorticoid antagonist via ERK activationNatural killer cells induce eosinophil activation and apoptosis.Transforming growth factor-beta-activated kinase 1 regulates natural killer cell-mediated cytotoxicity and cytokine production.Human NK cell lytic granules and regulation of their exocytosisRecruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells.ERK1/2, MEK1/2 and p38 downstream signalling molecules impaired in CD56 dim CD16+ and CD56 bright CD16 dim/- natural killer cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients.The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generationThrombospondin-1 is a CD47-dependent endogenous inhibitor of hydrogen sulfide signaling in T cell activationDysregulation of Protein Kinase Gene Expression in NK Cells from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients.The killer's kiss: the many functions of NK cell immunological synapses.Use of transfected Drosophila S2 cells to study NK cell activation.LFA-1 and CD2 synergize for the Erk1/2 activation in the Natural Killer (NK) cell immunological synapse.Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells.Signal transduction during activation and inhibition of natural killer cells.The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse.Molecular mechanisms of natural killer cell activation.IQGAP1: a regulator of intracellular spacetime relativity.Enhancement of NK cells proliferation and function by Shikonin.Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicity.Acute myeloid leukemia impairs natural killer cells through the formation of a deficient cytotoxic immunological synapse.NKG2D functions as an activating receptor on natural killer cells in the common marmoset (Callithrix jacchus).Ganoderma lucidum stimulates NK cell cytotoxicity by inducing NKG2D/NCR activation and secretion of perforin and granulysin.A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse.PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion.Role of gamma-secretase in human umbilical-cord derived mesenchymal stem cell mediated suppression of NK cell cytotoxicity.Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor ImmunityNKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease.Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction.IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity.Nuclear movement regulated by non-Smad Nodal signaling via JNK is associated with Smad signaling during zebrafish endoderm specification.NKG2D Signaling between Human NK Cells Enhances TACE-Mediated TNF-α Release.Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer.Neural differentiation of mesenchymal stem cells influences their chemotactic responses to stromal cell-derived factor-1α.Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity.IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells.
P2860
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P2860
JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
JNK MAP kinase activation is r ...... -mediated NK cell cytotoxicity
@ast
JNK MAP kinase activation is r ...... -mediated NK cell cytotoxicity
@en
type
label
JNK MAP kinase activation is r ...... -mediated NK cell cytotoxicity
@ast
JNK MAP kinase activation is r ...... -mediated NK cell cytotoxicity
@en
prefLabel
JNK MAP kinase activation is r ...... -mediated NK cell cytotoxicity
@ast
JNK MAP kinase activation is r ...... -mediated NK cell cytotoxicity
@en
P2093
P2860
P356
P1476
JNK MAP kinase activation is r ...... -mediated NK cell cytotoxicity
@en
P2093
Changlin Li
Hernan D Kopcow
Jack L Strominger
Joel N H Stern
Matthew Nicotra
P2860
P304
P356
10.1073/PNAS.0712310105
P407
P577
2008-02-19T00:00:00Z