Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
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BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathwayThree-Dimensional Microfluidic Tri-Culture Model of the Bone Marrow Microenvironment for Study of Acute Lymphoblastic LeukemiaHuman Organotypic Lung Tumor Models: Suitable For Preclinical 18F-FDG PET-ImagingHeparan sulfate proteoglycans mediate interstitial flow mechanotransduction regulating MMP-13 expression and cell motility via FAK-ERK in 3D collagenDynamic Microenvironment Induces Phenotypic Plasticity of Esophageal Cancer Cells Under Flow.Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1Interstitial fluid flow in cancer: implications for disease progression and treatment.Perspective: Flicking with flow: Can microfluidics revolutionize the cancer research?Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules.Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.Living in shear: platelets protect cancer cells from shear induced damage.BMP-4 induction of arrest and differentiation of osteoblast-like cells via p21 CIP1 and p27 KIP1 regulation.Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes.Implications of Lymphatic Transport to Lymph Nodes in Immunity and ImmunotherapyProstate cancer regulatory networksThe clinical impact of mean vessel size and solidity in breast carcinoma patients.Interstitial flow influences direction of tumor cell migration through competing mechanisms.Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of beta1-integrin.Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways.The physics of cancer: the role of physical interactions and mechanical forces in metastasis.By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization.Sensitivity analysis of an image-based solid tumor computational model with heterogeneous vasculature and porosityEffect of the glycocalyx layer on transmission of interstitial flow shear stress to embedded cells.Flow shear stress regulates endothelial barrier function and expression of angiogenic factors in a 3D microfluidic tumor vascular modelMicrofluidic Biopsy Trapping Device for the Real-Time Monitoring of Tumor Microenvironment.Mechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through Osterix pathway.Modulating the vascular behavior of metastatic breast cancer cells by curcumin treatmentIntegrin αvβ3 and CD44 pathways in metastatic prostate cancer cells support osteoclastogenesis via a Runx2/Smad 5/receptor activator of NF-κB ligand signaling axis.Novel phase I study combining G1 phase, S phase, and G2/M phase cell cycle inhibitors in patients with advanced malignanciesThree-dimensional microfluidic collagen hydrogels for investigating flow-mediated tumor-endothelial signaling and vascular organization.Different modes of endothelial-smooth muscle cell interaction elicit differential β-catenin phosphorylations and endothelial functions.TISSUE ENGINEERING PERFUSABLE CANCER MODELS.Perspectives on biological growth and remodeling.Microfluidics for research and applications in oncology.Heralding a new paradigm in 3D tumor modeling.Role for Mechanotransduction in Macrophage and Dendritic Cell Immunobiology.Optimization of flowrate for expansion of human embryonic stem cells in perfusion microbioreactors.Evaluation of specific delivery of chimeric phi29 pRNA/siRNA nanoparticles to multiple tumor cells.Regulatory network changes between cell lines and their tissues of origin.Continuously perfused microbubble array for 3D tumor spheroid model.
P2860
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P2860
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
@ast
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
@en
type
label
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
@ast
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
@en
prefLabel
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
@ast
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
@en
P2093
P2860
P356
P1476
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
@en
P2093
Cheng Allen Chang
Cheng-Kung Cheng
Chiuan-Ren Yeh
Ding-Yu Lee
Jeng-Jiann Chiu
Pei-Ling Lee
Shun-Fu Chang
Yu-Ming Yeh
P2860
P304
P356
10.1073/PNAS.0712353105
P407
P577
2008-02-29T00:00:00Z