A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence. - Wikidata - wikimedia - TriplyDB

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence.

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence.

http://www.wikidata.org/entity/Q36506922

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Interferon-λ: Immune Functions at Barrier Surfaces and Beyond Advances in norovirus biology Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain Discovery of a proteinaceous cellular receptor for a norovirus Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytes A broadly reactive one-step SYBR Green I real-time RT-PCR assay for rapid detection of murine norovirus.Efficient norovirus and reovirus replication in the mouse intestine requires microfold (M) cells.Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections.Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity.Type I interferons link viral infection to enhanced epithelial turnover and repair.Identification of immune and viral correlates of norovirus protective immunity through comparative study of intra-cluster norovirus strains.Murine norovirus 1 (MNV1) replication induces translational control of the host by regulating eIF4E activity during infection Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection.Viral immunity. Transkingdom control of viral infection and immunity in the mammalian intestine.Infection with the Persistent Murine Norovirus Strain MNV-S99 Suppresses IFN-Beta Release and Activation of Stat1 In Vitro.Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.Murine Norovirus Infection Variably Alters Atherosclerosis in Mice Lacking Apolipoprotein E Benign Rabbit Caliciviruses Exhibit Evolutionary Dynamics Similar to Those of Their Virulent Relatives Norovirus mechanisms of immune antagonism.Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases.Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus.Treatment with a Nucleoside Polymerase Inhibitor Reduces Shedding of Murine Norovirus in Stool to Undetectable Levels without Emergence of Drug-Resistant Variants.Viruses in Rodent Colonies: Lessons Learned from Murine Noroviruses.Recent advances in understanding norovirus pathogenesis.Pathology caused by persistent murine norovirus infection.Murine norovirus transcytosis across an in vitro polarized murine intestinal epithelial monolayer is mediated by M-like cells.Effects of murine norovirus on atherosclerosis in ldlr(-/-) mice depends on the timing of infection.Global Spread of Norovirus GII.17 Kawasaki 308, 2014-2016.Inactivation of Norovirus by Lemongrass Essential Oil Using a Norovirus Surrogate System.Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2.Isolated colon ischemia with norovirus infection in preterm babies: a case series.The mutation Glu151Asp in the B-component of the Bacillus cereus non-hemolytic enterotoxin (Nhe) leads to a diverging reactivity in antibody-based detection systems.Norovirus Cell Tropism Is Determined by Combinatorial Action of a Viral Non-structural Protein and Host Cytokine.Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche.Distinct Effects of Type I and III Interferons on Enteric Viruses.The Role of Interferon in Persistent Viral Infection: Insights from Murine Norovirus.Tropism for tuft cells determines immune promotion of norovirus pathogenesis.

P2860

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P2860

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence.

http://www.wikidata.org/entity/Q36506922

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2012 nî lūn-bûn

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A single-amino-acid change in ...... lonic tropism and persistence.

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A single-amino-acid change in ...... lonic tropism and persistence.

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A single-amino-acid change in ...... lonic tropism and persistence.

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A single-amino-acid change in ...... lonic tropism and persistence.

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P2093

Broc T McCune

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Calvin S Pohl

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David W Strong

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Timothy J Nice

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P2860

Norwalk virus shedding after experimental human infection

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophages

Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes

Has the microbiota played a critical role in the evolution of the adaptive immune system?

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4

Mechanisms of GII.4 norovirus persistence in human populations

In vitro proteolytic processing of the MD145 norovirus ORF1 nonstructural polyprotein yields stable precursors and products similar to those detected in calicivirus-infected cells.

Processing map and essential cleavage sites of the nonstructural polyprotein encoded by ORF1 of the feline calicivirus genome

A single amino acid substitution in the murine norovirus capsid protein is sufficient for attenuation in vivo.

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327-334

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10.1128/JVI.01864-12

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1

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87

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Herbert W. "Skip" Virgin

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232281561

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3536416

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