Mechanism of chloroform-induced renal toxicity: non-involvement of hepatic cytochrome P450-dependent metabolism
about
Application of an updated physiologically-based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and miceEscalating chronic kidney diseases of multi-factorial origin in Sri Lanka: causes, solutions, and recommendationsThe role of small-intestinal P450 enzymes in protection against systemic exposure of orally administered benzo[a]pyreneRole of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice.Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.The tissue-specific toxicity of methimazole in the mouse olfactory mucosa is partly mediated through target-tissue metabolic activation by CYP2A5Identification of structural alerts for liver and kidney toxicity using repeated dose toxicity dataRole of biotransformation in drug-induced toxicity: influence of intra- and inter-species differences in drug metabolism.Role of mammary epithelial and stromal P450 enzymes in the clearance and metabolic activation of 7,12-dimethylbenz(a)anthracene in mice.The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: utility of renal specific P450 reductase knockout mouse models.Regulation of intestinal cytochrome P450 expression by hepatic cytochrome P450: possible involvement of fibroblast growth factor 15 and impact on systemic drug exposure.Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations.Influence of sexual dimorphism on pulmonary inflammatory response in adult mice exposed to chloroform.Metabolism of halogenated alkanes by cytochrome P450 enzymes. Aerobic oxidation versus anaerobic reduction.Chronic, Recreational Chloroform-Induced Liver Injury
P2860
Q23909643-906B9953-67A1-4891-9459-E7996BD72138Q26850851-C22F51E5-BCAF-4346-83E0-71405449807CQ34028109-385F8A46-8CE9-4EAA-B4B8-B72261155314Q34405400-32EB5EFE-8405-44DD-9B57-F40375A29BC9Q34513706-F22AB4D7-001C-4B3C-ADA1-23E21CFD13DAQ35002458-4FC96A1E-2727-4478-94DE-8D502AD7ADBDQ35835738-2B5FDC64-8C84-4D75-881D-8F839467B496Q36362377-A1402194-154F-42CE-89E7-A89DCBA48102Q36889516-C8C87B86-C028-4A2F-9814-6F3FD63A5E8DQ37179150-0114828A-6851-4F03-93E5-54D17C70857DQ37405412-CBC819CA-C6DD-43D1-AB5C-CBE9D63ECC4AQ39242961-FAB21265-6614-47F6-A540-04F2A9FC2264Q41078128-5D41E390-B97E-4BDB-AE1E-A283041F012DQ46935577-ED2C08FD-9773-496F-BA1B-6D698ADAD340Q57114262-C6B36574-75CE-4076-96A1-02E0AB6587C5
P2860
Mechanism of chloroform-induced renal toxicity: non-involvement of hepatic cytochrome P450-dependent metabolism
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mechanism of chloroform-induce ...... rome P450-dependent metabolism
@ast
Mechanism of chloroform-induce ...... rome P450-dependent metabolism
@en
type
label
Mechanism of chloroform-induce ...... rome P450-dependent metabolism
@ast
Mechanism of chloroform-induce ...... rome P450-dependent metabolism
@en
prefLabel
Mechanism of chloroform-induce ...... rome P450-dependent metabolism
@ast
Mechanism of chloroform-induce ...... rome P450-dependent metabolism
@en
P2093
P2860
P1476
Mechanism of chloroform-induce ...... rome P450-dependent metabolism
@en
P2093
Cheng Fang
Hongxiu Luo
Kenneth Aldous
Meghan Doret
Melissa Behr
Weizhu Yang
Xinxin Ding
P2860
P356
10.1016/J.TAAP.2007.10.014
P577
2007-10-23T00:00:00Z