The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
about
Interleukin-2 receptor signaling: at the interface between tolerance and immunityPushing the envelope in the mTOR pathway: the second generation of inhibitorsRecent advances in understanding the molecular mechanisms of the development and function of Th17 cellsThe PD-1 pathway in tolerance and autoimmunitymTOR regulates memory CD8 T-cell differentiationmTOR Regulation of Lymphoid Cells in Immunity to PathogensT cell receptor signalling in the control of regulatory T cell differentiation and functionMilk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiationInhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and BeyondSignaling in T cells - is anything the m(a)TOR with the picture(s)?Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent TranslationInduced regulatory T cells: mechanisms of conversion and suppressive potentialKinase AKT controls innate immune cell development and functionRole of the PD-1 pathway in the immune responseThe mTOR pathway and integrating immune regulationIntegrating canonical and metabolic signalling programmes in the regulation of T cell responsesMicroRNA regulation of lymphocyte tolerance and autoimmunityCellular and molecular determinants for the development of natural and induced regulatory T cellsFOXO transcription factors throughout T cell biologyUbiquitin-dependent regulation of Foxp3 and Treg functionMicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and developmentTreg functional stability and its responsiveness to the microenvironmentNew immunotherapies targeting the PD-1 pathwayNature and nurture in Foxp3(+) regulatory T cell development, stability, and functionImmunotherapy in autoimmune type 1 diabetesThe PD1:PD-L1/2 Pathway from Discovery to Clinical ImplementationImmunometabolism of regulatory T cellsEarly Programming by Protein Intake: The Effect of Protein on Adiposity Development and the Growth and Functionality of Vital OrgansAging and immune function: molecular mechanisms to interventionsDifferential responses of human regulatory T cells (Treg) and effector T cells to rapamycinInflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivoSecretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cellsCutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cellsRegulatory T cells: mechanisms of differentiation and functionPD-L1 regulates the development, maintenance, and function of induced regulatory T cellsNovel Foxo1-dependent transcriptional programs control T(reg) cell functionInduction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery.A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice.Once a Treg, always a Treg?
P2860
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P2860
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
@ast
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
@en
type
label
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
@ast
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
@en
prefLabel
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
@ast
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
@en
P2093
P2860
P356
P1476
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
@en
P2093
Christophe Benoist
Diane Mathis
Sokol Haxhinasto
P2860
P304
P356
10.1084/JEM.20071477
P407
P577
2008-02-18T00:00:00Z