The antiapoptotic role of pregnane X receptor in human colon cancer cells. - Wikidata - wikimedia - TriplyDB

The antiapoptotic role of pregnane X receptor in human colon cancer cells.

The antiapoptotic role of pregnane X receptor in human colon cancer cells.

http://www.wikidata.org/entity/Q36512415

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Bile acids as endogenous etiologic agents in gastrointestinal cancer Cross-talk between bile acids and gastrointestinal tract for progression and development of cancer and its therapeutic implications Role of pregnane X receptor in chemotherapeutic treatment Targeting xenobiotic receptors PXR and CAR in human diseases PXR variants: the impact on drug metabolism and therapeutic responses Challenges predicting ligand-receptor interactions of promiscuous proteins: the nuclear receptor PXR Role of PXR in Hepatic Cancer: Its Influences on Liver Detoxification Capacity and Cancer Progression Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury.Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo.Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.Elucidating the 'Jekyll and Hyde' nature of PXR: the case for discovering antagonists or allosteric antagonists.CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells.Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Overcoming drug resistance by regulating nuclear receptors.Pregnane X receptor PXR activates the GADD45beta gene, eliciting the p38 MAPK signal and cell migration.Tissue-specific regulation of pregnane X receptor in cancer development and therapy.Activation of intestinal human pregnane X receptor protects against azoxymethane/dextran sulfate sodium-induced colon cancer Pregnane X receptor- and CYP3A4-humanized mouse models and their applications.Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells.MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer.Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivo Pregnane X Receptor Represses HNF4α Gene to Induce Insulin-Like Growth Factor-Binding Protein IGFBP1 that Alters Morphology of and Migrates HepG2 Cells.Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation.Expression of the PXR gene in various types of cancer and drug resistance Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer.PXR interaction with p53: a meeting of two masters Human pregnane X receptor compromises the function of p53 and promotes malignant transformation Pregnane X Receptor and Cancer: Context-Specificity is Key.A systematic analysis of predicted phosphorylation sites within the human pregnane X receptor protein.Xenobiotic Receptor-Mediated Regulation of Intestinal Barrier Function and Innate Immunity.Orphan nuclear receptors as targets for drug development.Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response.PXR cross-talks with internal and external signals in physiological and pathophysiological responses.Pharmacogenetics of the nuclear hormone receptors: the missing link between environment and drug effects?Advantages of cell-based high-volume screening assays to assess nuclear receptor activation during drug discovery.Human Xenobiotic Nuclear Receptor PXR Augments Mycobacterium tuberculosis Survival.Regulation of PXR and CAR by protein-protein interaction and signaling crosstalk.

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

http://www.wikidata.org/entity/Q36512415

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2007 nî lūn-bûn

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

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Molecular Endocrinology

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The antiapoptotic role of pregnane X receptor in human colon cancer cells.

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Jie Zhou

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Mingjie Liu

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Wen Xie

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Yonggong Zhai

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P2860

An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators

Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death

Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

The enzymes, regulation, and genetics of bile acid synthesis

Activator protein-1 and CCAAT/enhancer-binding protein mediated GADD153 expression is involved in deoxycholic acid-induced apoptosis

Mutations in the p53 gene occur in diverse human tumour types

Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity

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