uPA modulates the age-dependent effect of brain injury on cerebral hemodynamics through LRP and ERK MAPK.

uPA modulates the age-dependent effect of brain injury on cerebral hemodynamics through LRP and ERK MAPK.

Item
http://www.wikidata.org/entity/Q36512703
A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formationAdrenomedullin prevents sex-dependent impairment of autoregulation during hypotension after piglet brain injury through inhibition of ERK MAPK upregulation.SNP improves cerebral hemodynamics during normotension but fails to prevent sex dependent impaired cerebral autoregulation during hypotension after brain injury.Phenylephrine infusion prevents impairment of ATP- and calcium-sensitive potassium channel-mediated cerebrovasodilation after brain injury in female, but aggravates impairment in male, piglets through modulation of ERK MAPK upregulationGlucagon protects against impaired NMDA-mediated cerebrovasodilation and cerebral autoregulation during hypotension after brain injury by activating cAMP protein kinase A and inhibiting upregulation of tPA.TBI sex dependently upregulates ET-1 to impair autoregulation, which is aggravated by phenylephrine in males but is abrogated in females.tPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury.Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders.tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation during hypotension after traumatic brain injury through inhibition of ERK and JNK MAPKImpaired cerebral blood flow autoregulation during posttraumatic arterial hypotension after fluid percussion brain injury is prevented by phenylephrine in female but exacerbated in male piglets by extracellular signal-related kinase mitogen-activateEndothelin and the neurovascular unit in pediatric traumatic brain injury.Dopamine prevents impairment of autoregulation after traumatic brain injury in the newborn pig through inhibition of Up-regulation of endothelin-1 and extracellular signal-regulated kinase mitogen-activated protein kinase.Influence of Sex and ERK MAPK on the Pressure Reactivity Index in Newborn Piglets After Fluid Percussion InjuryRBC-coupled tPA Prevents Whereas tPA Aggravates JNK MAPK-Mediated Impairment of ATP- and Ca-Sensitive K Channel-Mediated Cerebrovasodilation After Cerebral PhotothrombosistPA-S(481)A prevents impairment of cerebrovascular autoregulation by endogenous tPA after traumatic brain injury by upregulating p38 MAPK and inhibiting ET-1.
P2860

uPA modulates the age-dependent effect of brain injury on cerebral hemodynamics through LRP and ERK MAPK.

Item
http://www.wikidata.org/entity/Q36512703
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
uPA modulates the age-dependen ...... mics through LRP and ERK MAPK.
@ast
uPA modulates the age-dependen ...... mics through LRP and ERK MAPK.
@en
type
label
uPA modulates the age-dependen ...... mics through LRP and ERK MAPK.
@ast
uPA modulates the age-dependen ...... mics through LRP and ERK MAPK.
@en
prefLabel
uPA modulates the age-dependen ...... mics through LRP and ERK MAPK.
@ast
uPA modulates the age-dependen ...... mics through LRP and ERK MAPK.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
uPA modulates the age-dependen ...... mics through LRP and ERK MAPK.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932