An intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.

An intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.

Item
http://www.wikidata.org/entity/Q36513131
Principles and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor.The luteinizing hormone receptor: insights into structure-function relationships and hormone-receptor-mediated changes in gene expression in ovarian cancer cells.Identification of key amino acid residues in a thyrotropin receptor monoclonal antibody epitope provides insight into its inverse agonist and antagonist properties.Bioluminescence resonance energy transfer studies reveal constitutive dimerization of the human lutropin receptor and a lack of correlation between receptor activation and the propensity for dimerization.Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics.Novel insights on thyroid-stimulating hormone receptor signal transduction.Target flexibility: an emerging consideration in drug discovery and design.A cell surface inactive mutant of the human lutropin receptor (hLHR) attenuates signaling of wild-type or constitutively active receptors via heterodimerization.Structural and functional plasticity of the luteinizing hormone/choriogonadotrophin receptor.Research resource: Update and extension of a glycoprotein hormone receptors web applicationFunctional characterization and pharmacological rescue of melanocortin-4 receptor mutations identified from obese patients.Modeling GPCR active state conformations: the β(2)-adrenergic receptor.
P2860

An intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.

Item
http://www.wikidata.org/entity/Q36513131
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
An intracellular loop (IL2) re ...... IL2 and helix 6, via helix 3.
@ast
An intracellular loop (IL2) re ...... IL2 and helix 6, via helix 3.
@en
type
label
An intracellular loop (IL2) re ...... IL2 and helix 6, via helix 3.
@ast
An intracellular loop (IL2) re ...... IL2 and helix 6, via helix 3.
@en
prefLabel
An intracellular loop (IL2) re ...... IL2 and helix 6, via helix 3.
@ast
An intracellular loop (IL2) re ...... IL2 and helix 6, via helix 3.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
An intracellular loop (IL2) re ...... n IL2 and helix 6, via helix 3
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932