Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.
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Wnt5a Signaling in CancerWnt5a induces ROR1 to complex with HS1 to enhance migration of chronic lymphocytic leukemia cells.Wnt5a Signaling in Normal and Cancer Stem CellsTargeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.Cirmtuzumab inhibits Wnt5a-induced Rac1 activation in chronic lymphocytic leukemia treated with ibrutinib.Targeting ROR1 identifies new treatment strategies in hematological cancers.ROR1 is a novel prognostic biomarker in patients with lung adenocarcinoma.High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia.Distinct Patterns of Stromal and Tumor Expression of ROR1 and ROR2 in Histological Subtypes of Epithelial Ovarian Cancer.Wnt5a induces ROR1 to associate with 14-3-3ζ for enhanced chemotaxis and proliferation of chronic lymphocytic leukemia cells.Wnt signalling pathways in chronic lymphocytic leukaemia and B-cell lymphomas.Wnt signaling in cardiovascular disease: opportunities and challenges.Molecular genetics and targeted therapy of WNT-related human diseases (Review).Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates.In-Silico Drug discovery approach targeting receptor tyrosine kinase-like orphan receptor 1 for cancer treatment.Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells.Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia.Wnt/β-catenin signaling during early vertebrate neural development.ROR2 receptor promotes the migration of osteosarcoma cells in response to Wnt5a.Interaction between ROR1 and MuSK activation complex in myogenic cells.Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1).Wnt Signaling in Hematological Malignancies.Silencing ROR1 and ROR2 inhibits invasion and adhesion in an organotypic model of ovarian cancer metastasis.Wnt5a induces ROR1 to recruit DOCK2 to activate Rac1/2 in chronic lymphocytic leukemia.Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit.A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib.Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma.Twist promotes tumor metastasis in basal-like breast cancer by transcriptionally upregulating ROR1.Role of WNT5A receptors FZD5 and RYK in prostate cancer cells.Critical molecular pathways in CLL therapy.Chronic lymphocytic leukaemia
P2860
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P2860
Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Wnt5a induces ROR1/ROR2 hetero ...... chemotaxis and proliferation.
@ast
Wnt5a induces ROR1/ROR2 hetero ...... chemotaxis and proliferation.
@en
type
label
Wnt5a induces ROR1/ROR2 hetero ...... chemotaxis and proliferation.
@ast
Wnt5a induces ROR1/ROR2 hetero ...... chemotaxis and proliferation.
@en
prefLabel
Wnt5a induces ROR1/ROR2 hetero ...... chemotaxis and proliferation.
@ast
Wnt5a induces ROR1/ROR2 hetero ...... chemotaxis and proliferation.
@en
P2093
P2860
P356
P1476
Wnt5a induces ROR1/ROR2 hetero ...... chemotaxis and proliferation.
@en
P2093
George F Widhopf
Liguang Chen
Ling Zhang
Rongrong Wu
Steven P Briggs
Suping Zhang
Thomas J Kipps
Zhouxin Shen
P2860
P304
P356
10.1172/JCI83535
P407
P50
P577
2015-12-21T00:00:00Z