Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
about
Uncommon cause of recurrent infectionsNeutrophils in type 1 diabetesAlways cleave up your mess: targeting collagen degradation to treat tissue fibrosisNeutrophil plasticity enables the development of pathological microenvironments: implications for cystic fibrosis airway diseaseChronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosisCigarette smoke drives small airway remodeling by induction of growth factors in the airway wall.Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3.Elastase, α1-proteinase inhibitor, and interleukin-8 in children and young adults with end-stage kidney disease undergoing continuous ambulatory peritoneal dialysis.Correlation of Plasma Neutrophil Elastase Activity and Endogenous Protease Inhibitor Levels with the Severity of Pre-eclampsia.Ischaemic stroke and the recanalization drug tissue plasminogen activator interfere with antibacterial phagocyte function.Effects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.Neutrophil elastase contributes to acute lung injury induced by bilateral nephrectomy.Bio-Revitalization: Effects of NASHA on Genes Involving Tissue Remodeling.Cervico-vaginal immunoglobulin G levels increase post-ovulation independently of neutrophils.Dual function inhibitors of relevance to chronic obstructive pulmonary diseaseA PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis.Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastaseEnhanced airway inflammation and remodeling in adenosine deaminase-deficient mice lacking the A2B adenosine receptor.Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis.Wound fluids: a window into the wound environment?The role of serpins in vertebrate immunity.Differential neutrophil activation in viral infections: Enhanced TLR-7/8-mediated CXCL8 release in asthma.Phase I Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis.A causal model of chronic obstructive pulmonary disease (COPD) risk.Lung injury following acute kidney injury: kidney-lung crosstalk.Circulating biomarkers of interstitial lung disease in systemic sclerosis.TGF-β1 as a therapeutic target for pulmonary fibrosis and COPD.Human airway trypsin-like protease, a serine protease involved in respiratory diseases.Cinnoline derivatives as human neutrophil elastase inhibitors.Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice.Synthesis and Pharmacological Evaluation of Indole Derivatives as Deaza Analogues of Potent Human Neutrophil Elastase Inhibitors.Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation.Relative α₁-anti-trypsin deficiency in systemic sclerosis.Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction.Effects of glucosamine and nucleotide association on fibroblast: extracellular matrix gene expression.Serum cystatin C and emphysema: results from the National Health and Nutrition Examination Survey (NHANES).Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase-9 (MMP-9) in leukocyte infiltration in a model of experimental peritonitis.Intermittent Hypoxia Contributes to the Lung Damage by Increased Oxidative Stress, Inflammation, and Disbalance in Protease/Antiprotease System.Reconstitution of human azurocidin catalytic triad and proteolytic activity by site-directed mutagenesis.
P2860
Q24596575-DAC98159-367F-4300-B7FD-EBEE3633325CQ26749490-227B15BD-7D87-45DB-BFD2-7611BBD8B68FQ26827393-1A5AD678-118C-4348-BAD8-4410BEE7B94EQ28071357-D219BBD1-EA8F-42DB-A50D-83DBEE7900A5Q28386104-E3764090-6676-4064-8DC9-E2544BCB90FAQ33258770-E863ADE3-93A9-428F-8277-8A6E02970599Q33522863-FDF871CC-B15D-472C-A1ED-0D7B10768822Q33624264-F2B888BB-C93E-4FA5-8D47-1662B7B834B1Q33666202-6E554423-9C27-431A-92AD-518A1E058395Q33922793-C749B575-1A39-4AFA-B026-EDE7EE31EB58Q34108214-F63D3D67-539C-44AA-A07D-41FB7DD3AFDFQ34149948-6AFBA605-6932-49BC-A442-7E32DFB1EECAQ34162310-2F6D7CB6-C2D6-416E-A490-0FDE41090BDDQ34481184-5C569CBE-1296-4041-A4C6-35B8854B6328Q34640774-4C950690-5006-4301-AEF4-D411AC497EB7Q35138428-AF7945EB-9255-471F-9A18-8205B4F4BD0CQ35981284-28F524ED-49B8-4A7C-96FD-6F041404ACDEQ36377312-08697800-B958-455D-A16C-208561166AA7Q36780402-C89D8723-0DDF-4D19-89B2-4D7F4B4D37D7Q36945415-0EBCA914-80BE-445F-9AA6-F83CAA454947Q37019696-63E9EDFA-39CA-4ADB-9CF3-6A37AB944E33Q37170955-D5248BC4-77F0-43FE-AA8D-1B6AEBD77EEBQ37663881-FA74B193-18F5-44C6-BD89-BC7E5FA0D060Q37700674-B1838564-7ECD-44A9-9C08-B00CB1D63E21Q37789415-A2839252-6480-41FB-981A-BD198C77CBABQ37883150-F18CAC50-16CF-4A68-8264-782C347E11C6Q38044387-EC44CC87-83CF-4D7D-B76E-47DDA8744F4CQ38177343-74CAB827-43F7-4014-8417-4A3DEC2A5FE0Q39149977-57CF27DD-ABC8-40EB-BCE9-F7E077F51CDCQ41099282-31D63EFF-86FD-4BCC-8EFE-3432086BD91EQ41319297-84417D72-C34F-400F-91F3-5511DB574581Q41451586-3122C236-D2EE-4E37-B065-4427FBE5CC58Q42094761-0C85973F-68F0-4438-B1D0-FDB775FF4AE4Q42102137-8A0C28E6-18E5-4327-8C16-9CACBAE0F00AQ42316383-6044A186-BF2E-4D49-A006-AC44C0337F7EQ43656933-93AE7CA5-D55D-427B-BDBB-C40A9F7C3037Q43877569-490D4DE3-D31E-4E47-8C9A-A5F3BD63E482Q46195101-7EF6BFF8-8F70-4515-99B3-390450CE2973Q46465518-5A058ACB-57E7-4278-808A-BDAB0D9A3214Q46483671-96716BFD-1345-4EB5-AAAA-961B0C3237CD
P2860
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
@ast
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
@en
type
label
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
@ast
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
@en
prefLabel
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
@ast
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
@en
P1476
Neutrophil elastase: mediator of extracellular matrix destruction and accumulation.
@en
P2093
Felix Chua
Geoffrey J Laurent
P304
P356
10.1513/PATS.200603-078AW
P577
2006-07-01T00:00:00Z