Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma.
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HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory DiseasesNKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple MyelomaSilencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancerValproic acid sensitizes pancreatic cancer cells to natural killer cell-mediated lysis by upregulating MICA and MICB via the PI3K/Akt signaling pathway.c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis.Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.γδ T cells and epigenetic drugs: A useful merger in cancer immunotherapy?The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myelomaNK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function declineCancer subclonal genetic architecture as a key to personalized medicine.Generation of soluble NKG2D ligands: proteolytic cleavage, exosome secretion and functional implications.Epigenetic modulating agents as a new therapeutic approach in multiple myeloma.Cancer-Induced Alterations of NK-Mediated Target Recognition: Current and Investigational Pharmacological Strategies Aiming at Restoring NK-Mediated Anti-Tumor Activityγδ T cells as a potential tool in colon cancer immunotherapy.Improving cancer immunotherapy with DNA methyltransferase inhibitors.How do tumor cells respond to HDAC inhibition?Methylation of NKG2D ligands contributes to immune system evasion in acute myeloid leukemia.The natural killer-activating receptor, NKG2D, on CD3+CD8+ T cells plays a critical role in identifying and killing autologous myeloma cells.Sodium valproate sensitizes non-small lung cancer A549 cells to γδ T-cell-mediated killing through upregulating the expression of MICA.Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis.Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integrationNatural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance.Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway.New prospects on the NKG2D/NKG2DL system for oncology.Synergistic effect of cytokine-induced killer cell with valproate inhibits growth of hepatocellular carcinoma cell in a mouse model.Platelet-derived TGF-β1 mediates the down-modulation of NKG2D expression and may be responsible for impaired natural killer (NK) cytotoxicity in women with endometriosis.NKG2D and Its Ligands: "One for All, All for One".Small-Molecule Targets in Tumor ImmunotherapyEpigenetic treatment of multiple myeloma mediates tumor intrinsic and extrinsic immunomodulatory effects
P2860
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P2860
Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Valproic acid upregulates NKG2 ...... ell-mediated lysis of myeloma.
@ast
Valproic acid upregulates NKG2 ...... ell-mediated lysis of myeloma.
@en
type
label
Valproic acid upregulates NKG2 ...... ell-mediated lysis of myeloma.
@ast
Valproic acid upregulates NKG2 ...... ell-mediated lysis of myeloma.
@en
prefLabel
Valproic acid upregulates NKG2 ...... ell-mediated lysis of myeloma.
@ast
Valproic acid upregulates NKG2 ...... ell-mediated lysis of myeloma.
@en
P2093
P2860
P356
P1433
P1476
Valproic acid upregulates NKG2 ...... ell-mediated lysis of myeloma.
@en
P2093
P2860
P304
P356
10.1593/NEO.121236
P577
2012-12-01T00:00:00Z