Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation.
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Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsAlterations of epigenetic signatures in hepatocyte nuclear factor 4α deficient mouse liver determined by improved ChIP-qPCR and (h)MeDIP-qPCR assays.Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells.MicroRNAs control hepatocarcinogenesis by regulating hepatocyte nuclear factor 4α-inflammatory signal feedback loops.Hepatocyte nuclear factor 4α induces a tendency of differentiation and activation of rat hepatic stellate cells.YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice.Regulation of hepatic microRNA expression by hepatocyte nuclear factor 4 alpha.Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networksMolecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte.Role of hepatocyte nuclear factor 4α (HNF4α) in cell proliferation and cancer.Regulation of hepatocyte identity and quiescence.Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference.Ultrastructural and immunohistochemical analysis of the 8-20 week human fetal pancreas.New Tools for Molecular Therapy of Hepatocellular Carcinoma.Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents.Liver-Specific Deletion of Integrin-Linked Kinase in Mice Attenuates Hepatotoxicity and Improves Liver Regeneration After Acetaminophen Overdose.The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction.Pro-regenerative signaling after acetaminophen-induced acute liver injury in mice identified using a novel incremental dose model.Induction of β-cell replication by a synthetic HNF4α antagonist.Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice.High fat diet-induced oxidative stress blocks hepatocyte nuclear factor 4α and leads to hepatic steatosis in mice.Protein arginine methyl transferase 1- and Jumonji C domain-containing protein 6-dependent arginine methylation regulate hepatocyte nuclear factor 4 alpha expression and hepatocyte proliferation in mice.Modulation of O-GlcNAc levels in the liver impacts acetaminophen-induced liver injury by affecting protein adduct formation and glutathione synthesis.Antitumour activity of an inhibitor of miR-34a in liver cancer with β-catenin-mutations.Activin A is a prominent autocrine regulator of hepatocyte growth arrest.DNA Damage Response Regulates Initiation of Liver Regeneration Following Acetaminophen Overdose.IL-23 enhances the malignant properties of hepatoma cells by attenuation of HNF4α.
P2860
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P2860
Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Hepatocyte-specific deletion o ...... ased hepatocyte proliferation.
@ast
Hepatocyte-specific deletion o ...... ased hepatocyte proliferation.
@en
type
label
Hepatocyte-specific deletion o ...... ased hepatocyte proliferation.
@ast
Hepatocyte-specific deletion o ...... ased hepatocyte proliferation.
@en
prefLabel
Hepatocyte-specific deletion o ...... ased hepatocyte proliferation.
@ast
Hepatocyte-specific deletion o ...... ased hepatocyte proliferation.
@en
P2093
P2860
P356
P1476
Hepatocyte-specific deletion o ...... ased hepatocyte proliferation.
@en
P2093
Chad Walesky
Ernest F Terwilliger
Genea Edwards
Prachi Borude
Sumedha Gunewardena
Udayan Apte
P2860
P304
P356
10.1152/AJPGI.00064.2012
P577
2012-10-25T00:00:00Z