Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model. - Wikidata - wikimedia - TriplyDB

Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model.

Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model.

http://www.wikidata.org/entity/Q36528798

about

Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo New generation humanized mice for virus research: comparative aspects and future prospects T-Regulatory Cells and Vaccination "Pay Attention and Do Not Neglect Them": Lessons from HIV and Cancer Vaccine Trials Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice Human hemato-lymphoid system mice: current use and future potential for medicine.An effective approach to prevent immune rejection of human ESC-derived allografts.Engineering the human thymic microenvironment to support thymopoiesis in vivo.Animal models for viral infection and cell exhaustion.Graft versus host disease in the bone marrow, liver and thymus humanized mouse model.A mechanistic, multiscale mathematical model of immunogenicity for therapeutic proteins: part 2-model applications.A mechanistic, multiscale mathematical model of immunogenicity for therapeutic proteins: part 1-theoretical model.CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs.PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads.The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment.Hypogammaglobulinemia in BLT humanized mice--an animal model of primary antibody deficiency.Human natural regulatory T cell development, suppressive function, and postthymic maturation in a humanized mouse model Macrophages prevent human red blood cell reconstitution in immunodeficient mice.Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever.Use of Humanized Mice to Study the Pathogenesis of Autoimmune and Inflammatory Diseases Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance.BLT humanized mice as a small animal model of HIV infection.Full reconstitution of human platelets in humanized mice after macrophage depletion.Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation Humanized Rag2(-/-)gammac(-/-) (RAG-hu) mice can sustain long-term chronic HIV-1 infection lasting more than a year.Mucosal HIV-1 transmission and prevention strategies in BLT humanized mice A model for personalized in vivo analysis of human immune responsiveness.Novel humanized murine models for HIV research.Humanized mouse models of HIV infection Modeling Human Leukemia Immunotherapy in Humanized Mice Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.HIV-specific CD8⁺ T-cell immunity in humanized bone marrow-liver-thymus mice Recent advances in humanized mice: accelerating the development of an HIV vaccine Humoral immunity in humanized mice: a work in progress.Achieving tolerance in pig-to-primate xenotransplantation: reality or fantasy.Use of humanized severe combined immunodeficient mice for human vaccine development.Induction of human T-cell tolerance to pig xenoantigens via thymus transplantation in mice with an established human immune system.BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection.CD47 in xenograft rejection and tolerance induction.

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Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model.

http://www.wikidata.org/entity/Q36528798

description

2008 nî lūn-bûn

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Akira Shimizu

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Katsuyoshi Habiro

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Megan Sykes

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Noriko Tonomura

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Yong-Guang Yang

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P2860

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

Clinical implications of the specialised B cell response to polysaccharide encapsulated pathogens

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance.

Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugates.

Lymphotoxin-alpha (LTalpha) supports development of splenic follicular structure that is required for IgG responses.

Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.

Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model.

Follicular dendritic cells and presentation of antigen and costimulatory signals to B cells.

The SCID-hu mouse as a model for HIV-1 infection.

Humanized mice: are we there yet?

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