Poleward microtubule flux mitotic spindles assembled in vitro
about
Kinesin-5: cross-bridging mechanism to targeted clinical therapyMitotic centromere-associated kinesin is important for anaphase chromosome segregationOpposing motor activities are required for the organization of the mammalian mitotic spindle poleProbing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.TPX2, A novel xenopus MAP involved in spindle pole organizationTwinkle, twinkle little star: photoswitchable fluorophores for super-resolution imagingAn ensemble of specifically targeted proteins stabilizes cortical microtubules in the human parasite Toxoplasma gondii.The Prp19 complex directly functions in mitotic spindle assemblyStatistical mechanics provides novel insights into microtubule stability and mechanism of shrinkagePericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome.The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work.Recovery, visualization, and analysis of actin and tubulin polymer flow in live cells: a fluorescent speckle microscopy study.Prophase microtubule arrays undergo flux-like behavior in mammalian cellsKinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cells.Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly.The distribution of polar ejection forces determines the amplitude of chromosome directional instability.Fast microtubule dynamics in meiotic spindles measured by single molecule imaging: evidence that the spindle environment does not stabilize microtubules.Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux.Microtubule plus-end dynamics in Xenopus egg extract spindles.Kif11 dependent cell cycle progression in radial glial cells is required for proper neurogenesis in the zebrafish neural tube.Maloriented bivalents have metaphase positions at the spindle equator with more kinetochore microtubules to one pole than to the other.Bipolarization and poleward flux correlate during Xenopus extract spindle assembly.Direct visualization of microtubule flux during metaphase and anaphase in crane-fly spermatocytes.Microtubule flux mediates poleward motion of acentric chromosome fragments during meiosis in insect spermatocytesA novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.Microtubule dynamics in Xenopus egg extracts.Directly probing the mechanical properties of the spindle and its matrix.Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindlesScreening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs.Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.Insights into the micromechanical properties of the metaphase spindleEg5 steps it up!Mechanism and function of poleward flux in Xenopus extract meiotic spindlesMembrane/microtubule tip attachment complexes (TACs) allow the assembly dynamics of plus ends to push and pull membranes into tubulovesicular networks in interphase Xenopus egg extracts.Kinetochore microtubule dynamics and the metaphase-anaphase transitionDSK1, a novel kinesin-related protein from the diatom Cylindrotheca fusiformis that is involved in anaphase spindle elongation.Anaphase A chromosome movement and poleward spindle microtubule flux occur At similar rates in Xenopus extract spindlesStu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body.Skeletor, a novel chromosomal protein that redistributes during mitosis provides evidence for the formation of a spindle matrixEg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix
P2860
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P2860
Poleward microtubule flux mitotic spindles assembled in vitro
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Poleward microtubule flux mitotic spindles assembled in vitro
@ast
Poleward microtubule flux mitotic spindles assembled in vitro
@en
type
label
Poleward microtubule flux mitotic spindles assembled in vitro
@ast
Poleward microtubule flux mitotic spindles assembled in vitro
@en
prefLabel
Poleward microtubule flux mitotic spindles assembled in vitro
@ast
Poleward microtubule flux mitotic spindles assembled in vitro
@en
P2860
P356
P1476
Poleward microtubule flux mitotic spindles assembled in vitro
@en
P2093
T J Mitchison
P2860
P304
P356
10.1083/JCB.112.5.941
P407
P577
1991-03-01T00:00:00Z