Structure of a new nervous system glycoprotein, Nr-CAM, and its relationship to subgroups of neural cell adhesion molecules
about
The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1Molecular characterization of the human transmembrane protein-tyrosine phosphatase delta. Evidence for tissue-specific expression of alternative human transmembrane protein-tyrosine phosphatase delta isoformsStructure of the axonal surface recognition molecule neurofascin and its relationship to a neural subgroup of the immunoglobulin superfamilyTargeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formationNeogenin, an avian cell surface protein expressed during terminal neuronal differentiation, is closely related to the human tumor suppressor molecule deleted in colorectal cancerNr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesisInduction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase betaThe Wnt Target Gene L1 in Colon Cancer Invasion and MetastasisBravo/Nr-CAM is closely related to the cell adhesion molecules L1 and Ng-CAM and has a similar heterodimer structureThe crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interactionColocalization of the homophilic binding site and the neuritogenic activity of the cell adhesion molecule L1 to its second Ig-like domain.Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neuritesInvolvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1Genes for the neuronal immunoglobulin domain cell adhesion molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12 and homologous human chromosomesMolecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segmentsThe close homologue of the neural adhesion molecule L1 (CHL1): patterns of expression and promotion of neurite outgrowth by heterophilic interactionsXenopus laevis neuronal cell adhesion molecule (nrcam): plasticity of a CAM in the developing nervous system.Concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis.Tissue-specific expression of the L1 cell adhesion molecule is modulated by the neural restrictive silencer element.Transient expression of neurofascin by oligodendrocytes at the onset of myelinogenesis: implications for mechanisms of axon-glial interaction.Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation.Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily.Outline structure of the human L1 cell adhesion molecule and the sites where mutations cause neurological disordersRegulation of axonal growth in the vertebrate nervous system by interactions between glycoproteins belonging to two subgroups of the immunoglobulin superfamily.Implications for the domain arrangement of axonin-1 derived from the mapping of its NgCAM binding site.The neural restrictive silencer element can act as both a repressor and enhancer of L1 cell adhesion molecule gene expression during postnatal development."CRASH"ing with the worm: insights into L1CAM functions and mechanisms.Neurite fasciculation mediated by complexes of axonin-1 and Ng cell adhesion moleculeCell adhesion molecules NgCAM and axonin-1 form heterodimers in the neuronal membrane and cooperate in neurite outgrowth promotionOverlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell developmentA direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons.An oligodendrocyte cell adhesion molecule at the site of assembly of the paranodal axo-glial junction.Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction.Different extracellular domains of the neural cell adhesion molecule (N-CAM) are involved in different functionsSticky situations: recent advances in control of cell adhesion during neuronal migrationNrCAM, a neuronal system cell-adhesion molecule, is induced in papillary thyroid carcinomas.Role of L1CAM for axon sprouting and branching.Regulation of adhesion by flexible ectodomains of IgCAMs.Jarid2 is among a set of genes differentially regulated by Nkx2.5 during outflow tract morphogenesis.Cell adhesion molecule L1 in folded (horseshoe) and extended conformations.
P2860
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P2860
Structure of a new nervous system glycoprotein, Nr-CAM, and its relationship to subgroups of neural cell adhesion molecules
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Structure of a new nervous sys ...... neural cell adhesion molecules
@ast
Structure of a new nervous sys ...... neural cell adhesion molecules
@en
type
label
Structure of a new nervous sys ...... neural cell adhesion molecules
@ast
Structure of a new nervous sys ...... neural cell adhesion molecules
@en
prefLabel
Structure of a new nervous sys ...... neural cell adhesion molecules
@ast
Structure of a new nervous sys ...... neural cell adhesion molecules
@en
P2093
P2860
P356
P1476
Structure of a new nervous sys ...... neural cell adhesion molecules
@en
P2093
B A Cunningham
M P Burgoon
P2860
P304
P356
10.1083/JCB.113.6.1399
P407
P577
1991-06-01T00:00:00Z