Targeted disruption of the ABP-120 gene leads to cells with altered motility.
about
Novel actin crosslinker superfamily member identified by a two step degenerate PCR procedureActin binding domains direct actin-binding proteins to different cytoskeletal locations.The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton'Dicty dynamics': Dictyostelium motility as persistent random motion.Both contractile axial and lateral traction force dynamics drive amoeboid cell motilityFilamin repeat segments required for photosensory signalling in Dictyostelium discoideum.Expression patterns of cell-type-specific genes in Dictyostelium.A cell number-counting factor regulates the cytoskeleton and cell motility in Dictyostelium.Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants.Cell-substrate interactions and locomotion of Dictyostelium wild-type and mutants defective in three cytoskeletal proteins: a study using quantitative reflection interference contrast microscopy.New insights into the role of the cytoskeleton in phagocytosis of Entamoeba histolytica.Insights into morphogenesis from a simple developmental system.A 27,000-D core of the Dictyostelium 34,000-D protein retains Ca(2+)-regulated actin cross-linking but lacks bundling activityDictyostelium discoideum mutants with conditional defects in phagocytosis.Genetic deletion of ABP-120 alters the three-dimensional organization of actin filaments in Dictyostelium pseudopods.Dictyostelium discoideum cells lacking the 34,000-dalton actin-binding protein can grow, locomote, and develop, but exhibit defects in regulation of cell structure and movement: a case of partial redundancy.Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation.Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium.Modulation of tensin and vimentin expression in chick embryo developing cartilage and cultured differentiating chondrocytes.Combining experiments and modelling to understand size regulation in Dictyostelium discoideumInducible expression of calmodulin antisense RNA in Dictyostelium cells inhibits the completion of cytokinesis.Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants.Cell migration in multicellular environments.Dictyostelium mutants lacking the cytoskeletal protein coronin are defective in cytokinesis and cell motility.Non-Brownian dynamics and strategy of amoeboid cell locomotion.Interaction of a Dictyostelium member of the plastin/fimbrin family with actin filaments and actin-myosin complexes.Chemotaxis to cAMP and slug migration in Dictyostelium both depend on migA, a BTB protein.Structure/function studies on cytoskeletal proteins in Dictyostelium amoebae as a paradigm.Effects of extracellular matrix components on cell locomotion.Role of actin polymerization in cell locomotion: molecules and models.Inhibition of actin filament depolymerization by the Dictyostelium 30,000-D actin-bundling proteinA talin homologue of Dictyostelium rapidly assembles at the leading edge of cells in response to chemoattractant.Mathematically modelling the effects of counting factor in Dictyostelium discoideum.A novel Amoeba proteus 120 kDa actin-binding protein with only 1 filamin repeat and a coiled-coil region.Ponticulin plays a role in the positional stabilization of pseudopods.Filamin-regulated F-actin assembly is essential for morphogenesis and controls phototaxis in Dictyostelium.Gamete fusion and cytokinesis preceding zygote establishment in the sexual process of Dictyostelium discoideum.
P2860
Q28295252-A2E6CC5C-809B-4BE7-8526-2EC745038967Q30481568-10CE67DA-2B67-4B8D-ACEC-279289FDB78EQ30501999-AA88AC4F-161C-4797-883B-E298647E03E5Q30503160-BFF48C7C-76D2-4DA3-AF95-19D2BBF49393Q30576931-ED22E5D2-A38F-482C-95E5-DE90263C0755Q30838101-03BEA96C-62B9-4DB1-86E9-7319C21EB760Q33946660-A21D085D-4F4F-44F1-8F87-013836A37EA6Q34009399-0A85D9BA-F615-4444-9877-509C1E12481AQ34017280-8699DF1E-2455-4D15-A393-B9B06502C649Q34128776-18C31AFF-532A-4870-81EA-88E43ACACD08Q34156233-D469E912-E4CA-4433-AAFA-352A0C382697Q35825855-8BBF26AA-AF19-4885-98F2-7D6DA736AEA4Q36233046-CE61598A-A77A-4CEF-96F6-7886CD8725DBQ36234424-E9B43CF6-655E-4445-B8D7-73016D6F710BQ36235376-631E13AB-357C-4E51-9E9E-3356E65D774EQ36256894-E6E9C891-B04C-4684-A351-B4A7B1D4B8ABQ36322541-6FE60CF4-62ED-4D06-9DA4-61A8563017CEQ36534955-5597408F-6163-403F-8BFB-E1C31D83602DQ36754018-93336730-AA6A-4AEE-BBB9-D7AA556DE903Q36824110-C4E4DC91-B4BA-400E-8545-17C8D4E82EF3Q37375349-AEAC6315-397E-417E-8A9A-3175D331FD42Q37380971-E20E0420-97B3-4AE3-A9FC-14A53AAF5703Q37876444-85D400D0-BCCB-4CEE-B2B6-15AE7CF3A9F2Q38323008-066C1586-0D99-4450-8C5E-6791293CEDA0Q39334786-DA1D0963-22CF-4B71-B97E-ECB4202DDF32Q40243219-35038880-0EA7-42CE-9D76-29A17D6CB663Q40387725-D4FE0C2F-387E-4B19-B52C-595F3C8FF9D2Q40463733-81184CC9-46F5-435B-B792-935C7907E148Q40806873-6BEC54C4-0CA2-4689-A67E-54B4DF8907B3Q40821929-669CAB9E-7B84-4C6D-BC96-C68177091FD1Q41999612-4D97C2E6-F0E2-4E6B-B8E8-6F18898C438DQ42019044-4A101ECE-A15B-4C46-8D44-9DF1E2162BCCQ42429442-0C130CDD-7907-4528-945D-04B4C14ED3CEQ42618466-F07D8694-850F-4E88-B93C-F3FF87EA9E7AQ42771841-97925227-58D3-4C0C-9F4D-89E16EE8AAA2Q50707343-29EF0FBB-45DB-4172-B918-D03A20C75084Q50776393-488D9249-115A-47B2-A2B6-3111AD8789DC
P2860
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
@ast
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
@en
type
label
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
@ast
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
@en
prefLabel
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
@ast
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
@en
P2093
P2860
P356
P1476
Targeted disruption of the ABP-120 gene leads to cells with altered motility.
@en
P2093
P2860
P304
P356
10.1083/JCB.116.4.943
P407
P577
1992-02-01T00:00:00Z