Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.
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Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast CarcinomaTranscriptional activation of the cyclin A gene by the architectural transcription factor HMGA2Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcriptionDisrupting the pairing between let-7 and Hmga2 enhances oncogenic transformationHigh mobility group a proteins as tumor markersPhosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytesTranscriptional regulation by targeted expression of architectural transcription factor high mobility group A2 in salivary glands of transgenic miceHmga1/Hmga2 double knock-out mice display a "superpygmy" phenotypeDynamics of gene-modified progenitor cells analyzed by tracking retroviral integration sites in a human SCID-X1 gene therapy trialHMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels.Downregulation of HMGA-targeting microRNAs has a critical role in human pituitary tumorigenesis.Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemiaMolecular basis of clonal expansion of hematopoiesis in 2 patients with paroxysmal nocturnal hemoglobinuria (PNH).HMGB1 in health and disease.Regulation of microRNA expression by HMGA1 proteins.Epigenetic Mechanisms Leading to Overexpression of HMGA Proteins in Human Pituitary Adenomas.Critical role of HMGA proteins in cancer cell chemoresistance.Human natural killer cell development.HMG chromosomal proteins in development and disease.Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation.Human papilloma virus-dependent HMGA1 expression is a relevant step in cervical carcinogenesisTranslocations in epithelial cancers.Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation.HMGA proteins as modulators of chromatin structure during transcriptional activation.Peripheral T-cell and NK cell lymphoproliferative disorders: cell of origin, clinical and pathological implications.Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells.The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression.High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2).High-mobility group A1 proteins are overexpressed in human leukaemias.Thyroid cell transformation requires the expression of the HMGA1 proteins.Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes.HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas.A new role for the oncogenic high-mobility group A2 transcription factor in myogenesis of embryonic stem cells.Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models.The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1.Increased serum levels of interleukin-15 correlate with negative prognostic factors in extranodal NK/T cell lymphoma.Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.Dysregulation and overexpression of HMGA2 in myelofibrosis with myeloid metaplasia.HAND1 gene expression is negatively regulated by the High Mobility Group A1 proteins and is drastically reduced in human thyroid carcinomas
P2860
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P2860
Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Onset of natural killer cell l ...... of the IL-2 and IL-15 pathway.
@ast
Onset of natural killer cell l ...... of the IL-2 and IL-15 pathway.
@en
type
label
Onset of natural killer cell l ...... of the IL-2 and IL-15 pathway.
@ast
Onset of natural killer cell l ...... of the IL-2 and IL-15 pathway.
@en
prefLabel
Onset of natural killer cell l ...... of the IL-2 and IL-15 pathway.
@ast
Onset of natural killer cell l ...... of the IL-2 and IL-15 pathway.
@en
P2093
P2860
P50
P356
P1476
Onset of natural killer cell l ...... of the IL-2 and IL-15 pathway.
@en
P2093
A J Klein-Szanto
S Battista
T A Waldmann
P2860
P304
P356
10.1073/PNAS.141224998
P407
P577
2001-06-26T00:00:00Z