RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
about
Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickaseHighly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system.Recent Developments Using Small Molecules to Target RAD51: How to Best Modulate RAD51 for Anticancer Therapy?Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJGenome Editing with CRISPR-Cas9: Can It Get Any Better?Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cellsIdentification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression.A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular ResearchUltra-superovulation for the CRISPR-Cas9-mediated production of gene-knockout, single-amino-acid-substituted, and floxed mice.CRISPR RNA-guided FokI nucleases repair a PAH variant in a phenylketonuria model.Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair.Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryosEfficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavageOne-Step Biallelic and Scarless Correction of a β-Thalassemia Mutation in Patient-Specific iPSCs without Drug Selection.CRISPR/Cas9-Mediated Genome Editing Corrects Dystrophin Mutation in Skeletal Muscle Stem Cells in a Mouse Model of Muscle Dystrophy.Efficient generation of mice carrying homozygous double-floxp alleles using the Cas9-Avidin/Biotin-donor DNA system.Small molecules enhance CRISPR/Cas9-mediated homology-directed genome editing in primary cells.Small molecules and their role in effective preclinical target validation.CRISPR Editing in Biological and Biomedical Investigation.Developmental history and application of CRISPR in human disease.CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy.Advances in the delivery of RNA therapeutics: from concept to clinical reality.Organoid technologies meet genome engineering.CRISPR/Cas9 for plant genome editing: accomplishments, problems and prospects.Use of genome-editing tools to treat sickle cell disease.Regulation of Single-Strand Annealing and its Role in Genome Maintenance.Clustered Regularly Interspaced Short Palindromic Repeats: Challenges in Treating Retinal Disease.CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.Precision genome editing in the CRISPR era.The CRISPR/Cas9 system: Their delivery, in vivo and ex vivo applications and clinical development by startups.Genome and Epigenome Editing in Mechanistic Studies of Human Aging and Aging-Related Disease.A Catalog of Regulatory Sequences for Trait Gene for the Genome Editing of Wheat.Production of immunodeficient rabbits by multiplex embryo transfer and multiplex gene targetingRabbit models for biomedical research revisited via genome editing approaches.Genome Editing: The Recent History and Perspective in Cardiovascular Diseases.CRISPR is knocking on barn door.Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing.Assembly of CRISPR ribonucleoproteins with biotinylated oligonucleotides via an RNA aptamer for precise gene editing.CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects.Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection.
P2860
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P2860
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
@ast
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
@en
type
label
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
@ast
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
@en
prefLabel
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
@ast
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
@en
P2093
P2860
P356
P1476
RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
@en
P2093
Dongshan Yang
Jifeng Zhang
Tianqing Zhu
Y Eugene Chen
P2860
P2888
P356
10.1038/NCOMMS10548
P407
P577
2016-01-28T00:00:00Z