Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells.
about
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique proteinA novel role for DNA single-strand breaks in senescence and neoplastic escape of epithelial cells.Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo.ATF6α regulates morphological changes associated with senescence in human fibroblasts.HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs).Chemical screening identifies ATM as a target for alleviating senescence.Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses?Induction of senescence in primary glioblastoma cells by serum and TGFβ.Senescence is a Spi1-induced anti-proliferative mechanism in primary hematopoietic cells.Molecular Genetic Analysis of Human Endometrial Mesenchymal Stem Cells That Survived Sublethal Heat Shock.SIRT1 regulates Mxd1 during malignant melanoma progression.Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence.miR-200a Modulates the Expression of the DNA Repair Protein OGG1 Playing a Role in Aging of Primary Human Keratinocytes.The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration
P2860
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P2860
Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Defective DNA single-strand br ...... ic escape of epithelial cells.
@ast
Defective DNA single-strand br ...... ic escape of epithelial cells.
@en
type
label
Defective DNA single-strand br ...... ic escape of epithelial cells.
@ast
Defective DNA single-strand br ...... ic escape of epithelial cells.
@en
prefLabel
Defective DNA single-strand br ...... ic escape of epithelial cells.
@ast
Defective DNA single-strand br ...... ic escape of epithelial cells.
@en
P2093
P2860
P356
P1476
Defective DNA single-strand br ...... tic escape of epithelial cells
@en
P2093
Albin Pourtier
Elisa Tomellini
Emeric Deruy
Eric Gilson
Fatima Bouali
Joe Nassour
Nathalie Martin
Nicolas Malaquin
Nicolas Wernert
Olivier Pluquet
P2860
P2888
P356
10.1038/NCOMMS10399
P407
P577
2016-01-29T00:00:00Z