Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer. - Wikidata - wikimedia - TriplyDB

Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer.

Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer.

http://www.wikidata.org/entity/Q36544980

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Bone metastases: When and how lung cancer interacts with bone Immune regulation of bone metastasis Myeloid-derived suppressor cells as therapeutic target in hematological malignancies Myeloid-derived suppressor cells in cancer: therapeutic, predictive, and prognostic implications Regulation of tumor metastasis by myeloid-derived suppressor cells Bone specific immunity and its impact on metastasis Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected Orchestration of angiogenesis by immune cells The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.MicroRNAs in the control of metastatic bone disease.Dissecting the role of bone marrow stromal cells on bone metastases.Osteoclasts: more than 'bone eaters'.Extracellular Membrane Vesicles Derived from 143B Osteosarcoma Cells Contain Pro-Osteoclastogenic Cargo: A Novel Communication Mechanism in Osteosarcoma Bone Microenvironment.Human osteoclasts are inducible immunosuppressive cells in response to T cell-derived IFN-γ and CD40 ligand in vitro Tungsten targets the tumor microenvironment to enhance breast cancer metastasis Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases Bone-immune cell crosstalk: bone diseases.Bone marrow as a metastatic niche for disseminated tumor cells from solid tumors.Myeloid lineage skewing due to exacerbated NF-κB signaling facilitates osteopenia in Scurfy mice.Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer A core of kinase-regulated interactomes defines the neoplastic MDSC lineage.Myeloid-Derived Suppressor Cells Express Bruton's Tyrosine Kinase and Can Be Depleted in Tumor-Bearing Hosts by Ibrutinib Treatment.Osteoclasts-Key Players in Skeletal Health and Disease.Myeloid-derived suppressor cells as osteoclast progenitors: a novel target for controlling osteolytic bone metastasis Down-regulation of PLCγ2-β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer.Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma.Location of tumor affects local and distant immune cell type and number Contributions of the host microenvironment to cancer-induced bone disease.Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies.Integrating new discoveries into the "vicious cycle" paradigm of prostate to bone metastases.Bone and the innate immune system.Induction of osteoclast progenitors in inflammatory conditions: key to bone destruction in arthritis.Immunological dysregulation in multiple myeloma microenvironment.Myeloid-derived suppressor cells: their role in the pathophysiology of hematologic malignancies and potential as therapeutic targets.Myeloid-derived suppressor cells in multiple myeloma: pre-clinical research and translational opportunities.The Impact of Immune System in Regulating Bone Metastasis Formation by Osteotropic Tumors.The Bone Microenvironment: a Fertile Soil for Tumor Growth.One microenvironment does not fit all: heterogeneity beyond cancer cells.Bone marrow myeloid cells in regulation of multiple myeloma progression.

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P2860

Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer.

http://www.wikidata.org/entity/Q36544980

description

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Myeloid-derived suppressor cel ...... ng bone loss in breast cancer.

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Myeloid-derived suppressor cel ...... ng bone loss in breast cancer.

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Myeloid-derived suppressor cel ...... ng bone loss in breast cancer.

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Myeloid-derived suppressor cel ...... ng bone loss in breast cancer.

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0008-5472.CAN-12-2202

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Cancer Research

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Myeloid-derived suppressor cel ...... ng bone loss in breast cancer.

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Anandi Sawant

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Brittney A Harris

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Carnella M Lee

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Jessy Deshane

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Joel Jules

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Selvarangan Ponnazhagan

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Xu Feng

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P2860

Myeloid-derived suppressor cells: linking inflammation and cancer

Myeloid-derived suppressor cells as regulators of the immune system

Metastatic bone disease: clinical features, pathophysiology and treatment strategies

Coordinated regulation of myeloid cells by tumours

Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways.

Genetic ablation of CD68 results in mice with increased bone and dysfunctional osteoclasts.

Phase II trial of gemcitabine/carboplatin (plus trastuzumab in HER2-positive disease) in patients with metastatic breast cancer.

Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

Tumor-infiltrating, myeloid-derived suppressor cells inhibit T cell activity by nitric oxide production in an intracranial rat glioma + vaccination model.

Mechanisms of bone metastasis.

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10.1158/0008-5472.CAN-12-2202

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2

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3548966

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